DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment spirit and CG6592

DIOPT Version :9

Sequence 1:	NP_001162707.1	Gene:	spirit / 31797	FlyBaseID:	FBgn0030051	Length:	393	Species:	Drosophila melanogaster
Sequence 2:	NP_648016.1	Gene:	CG6592 / 38687	FlyBaseID:	FBgn0035669	Length:	438	Species:	Drosophila melanogaster

Alignment Length:	263	Identity:	80/263 - (30%)
Similarity:	122/263 - (46%)	Gaps:	33/263 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   132 VVGGMPTRPREFPFMAALGWRSNFDQRIYYRCGGALIANNFVLTAAHCADLGGEPPSQVRLGGDN 196
            :.||....|..||:.  :|......:.:|: |||:||::..|:|||||.|:...  :.|.||.:.
  Fly   123 IFGGDVGNPHCFPYQ--VGMLLQRPKGLYW-CGGSLISDKHVITAAHCVDMAKR--ALVFLGANE 182

  Fly   197 LTLTEGEDISIRRVI------IHPDYSASTAYNDIALLELETAAK------PELKPTCIWTQKEV 249
            :...: |...:|.::      |:|.::.....:|||::.|..|..      |...|...:..:..
  Fly   183 IKNAK-EKGQVRLMVPSENFQIYPTWNPKRLKDDIAIVRLPHAVSFNERIHPIQLPKRHYEYRSF 246

  Fly   250 TNTLVTAIGYGQ--TSFAGLSSAQLLKVPLKSVSNEECQHHYQKDQLAQGVLGTQMCAGDITGER 312
            .|.|..|.|:|:  |....:|:. |..|.|:.:....|     |........||.:|... ...|
  Fly   247 KNKLAIASGWGRYATGVHAISNV-LRYVQLQIIDGRTC-----KSNFPLSYRGTNICTSG-RNAR 304

  Fly   313 DTCQGDSGGPLLMQ--DGLLGYVVGITSLGQ--GCASGPPSVYTRVSSFVDWI--EGIVWPAQQV 371
            .||.|||||||::|  ......:|||||.|.  ||..|.|:.:|:|:|::|||  |..|...|..
  Fly   305 STCNGDSGGPLVLQRRHSKKRVLVGITSFGSIYGCDRGYPAAFTKVASYLDWISDETGVSAHQDT 369

  Fly   372 TNA 374
            |.|
  Fly   370 TEA 372

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
spirit	NP_001162707.1	CLIP	51..98	CDD:197829
		Tryp_SPc	132..364	CDD:238113	76/251 (30%)
		Tryp_SPc	132..361	CDD:214473	73/246 (30%)
CG6592	NP_648016.1	Tryp_SPc	122..357	CDD:214473	73/246 (30%)
CG6592	NP_648016.1	Tryp_SPc	123..359	CDD:238113	75/248 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437055
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940