DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment spirit and CG3700

DIOPT Version :9

Sequence 1:	NP_001162707.1	Gene:	spirit / 31797	FlyBaseID:	FBgn0030051	Length:	393	Species:	Drosophila melanogaster
Sequence 2:	NP_611736.1	Gene:	CG3700 / 37640	FlyBaseID:	FBgn0034796	Length:	360	Species:	Drosophila melanogaster

Alignment Length:	350	Identity:	118/350 - (33%)
Similarity:	163/350 - (46%)	Gaps:	63/350 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 GTCRRM--EDCPSALNGWLERRESPKTCYFVRFDHYVCCAPAVAPI-----------VTRSSQQA 112
            |.|:.:  .|||...  :.:.....:..|...|:..|||     ||           .||..::.
  Fly    28 GECKELTPSDCPVIF--YNQHLIGAEVKYCDEFNDIVCC-----PIPLDHQNLKPAEQTRPFEKQ 85

  Fly   113 CNELNKVSKVKEIDEFFVSVVGGMPTRPREFPFMAALGW----RSNFDQRIYYRCGGALIANNFV 173
            |.:.|:|....:...|   :|||.....:||||||.:|.    :|..|  |.:.|||:::...||
  Fly    86 CKQYNEVRSACQSTPF---IVGGTKASGKEFPFMALIGTHRPNKSKSD--INWDCGGSVVHPKFV 145

  Fly   174 LTAAHCADLG-----------GEPPSQVRLG--GDNLTLTEG--EDISIRRVIIHPDYSASTA-- 221
            ||||||.:..           ..|...||||  ..|.|..:.  :|..:...::||.|.....
  Fly   146 LTAAHCLETDESKAERLDPNFDSPKFVVRLGELDYNSTTDDALVQDFRVVNYVVHPGYDTEDEEQ 210

  Fly   222 --YNDIALLELETAAK--PELKPTCIWTQKEVTNTLVTAIGYGQTSFAGLSSAQLLKVPLKSVSN 282
              .|||||:||:..|:  ..:...|:..........|||.|:|.|: .|:.|:.||||.|:..|:
  Fly   211 GFKNDIALVELDRKAEFNDHVAAVCLPPDSGNDVQQVTAAGWGFTA-DGVKSSHLLKVNLQRFSD 274

  Fly   283 EECQH--HYQKDQLAQGVLGTQMCAGDITGERDTCQGDSGGPLLMQDGL---LGYVVGITSLGQG 342
            |.||.  .:..|      ..||.|||.::.:.|||.||||||:.:|..|   |..|:||.|.|..
  Fly   275 EVCQKRLRFSID------TRTQFCAGSMSSQADTCNGDSGGPIFVQHPLYPCLKQVIGIVSYGLV 333

  Fly   343 CAS-GPPSVYTRVSSFVDWIEGIVW 366
            |.| |.|||||:|..:.||||.|||
  Fly   334 CGSQGLPSVYTKVHLYTDWIESIVW 358

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
spirit	NP_001162707.1	CLIP	51..98	CDD:197829	9/38 (24%)
		Tryp_SPc	132..364	CDD:238113	97/262 (37%)
		Tryp_SPc	132..361	CDD:214473	94/259 (36%)
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	97/262 (37%)
CG3700	NP_611736.1	Tryp_SPc	102..353	CDD:214473	94/259 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D105391at6960
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.920