Protein Alignment spirit and TMPRSS11E

DIOPT Version :10

• Sequence 1: NP_572492.1
• Gene: spirit / 31797
• FlyBaseID: FBgn0030051
• Length: 393
• Species: Drosophila melanogaster
• Sequence 2: NP_054777.2
• Gene: TMPRSS11E / 28983
• HGNCID: 24465
• Length: 423
• Species: Homo sapiens
• Alignment Length: 300
• Identity: 79/300 - (26%)
• Similarity: 117/300 - (39%)
• Gaps: 83/300 - (27%)

  Fly    92 DHYV--CCAPAVAPIVTRSSQQACNELNKVSKVKEIDEFFVSVVGGMPTRPREFPFMAALGWRSN 154
            |.|:  ||.       ||.|:.....|.              :|||......|:|:.|:|.|..:
Human   171 DSYLNHCCG-------TRRSKTLGQSLR--------------IVGGTEVEEGEWPWQASLQWDGS 214

  Fly   155 FDQRIYYRCGGALIANNFVLTAAHCADLGGEP------------PSQVRLGGDNLTLTEGEDISI 207
                  :|||..||...::::||||......|            ||:::.|             :
Human   215 ------HRCGATLINATWLVSAAHCFTTYKNPARWTASFGVTIKPSKMKRG-------------L 260

  Fly   208 RRVIIHPDYSASTAYNDIALLELETA--------------AKPELKPTCIWTQKEVTNTLVTAIG 258
            ||:|:|..|...:...||:|.||.:.              |..|.:|          ..::...|
Human   261 RRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPDASYEFQP----------GDVMFVTG 315

  Fly   259 YGQTSFAGLSSAQLLKVPLKSVSNEECQHHYQKDQLAQGVLGTQMCAGDITGERDTCQGDSGGPL 323
            :|.....|.|...|.:..:..:....|.   :.......:....:|||.:.|:.|.|||||||||
Human   316 FGALKNDGYSQNHLRQAQVTLIDATTCN---EPQAYNDAITPRMLCAGSLEGKTDACQGDSGGPL 377

  Fly   324 LMQDGL-LGYVVGITSLGQGCAS-GPPSVYTRVSSFVDWI 361
            :..|.. :.|:.||.|.|..||. ..|.|||||::..|||
Human   378 VSSDARDIWYLAGIVSWGDECAKPNKPGVYTRVTALRDWI 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spirit	NP_572492.1	CLIP	51..98	CDD:197829	3/7 (43%)
		Tryp_SPc	132..364	CDD:238113	70/257 (27%)
TMPRSS11E	NP_054777.2	SEA	51..147	CDD:460188
		Tryp_SPc	192..420	CDD:238113	70/257 (27%)