DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment spirit and try-3

DIOPT Version :9

Sequence 1:	NP_001162707.1	Gene:	spirit / 31797	FlyBaseID:	FBgn0030051	Length:	393	Species:	Drosophila melanogaster
Sequence 2:	NP_001367393.1	Gene:	try-3 / 183420	WormBaseID:	WBGene00006621	Length:	313	Species:	Caenorhabditis elegans

Alignment Length:	256	Identity:	79/256 - (30%)
Similarity:	120/256 - (46%)	Gaps:	35/256 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   163 CGGALIANNFVLTAAHCA-DLGGEPPSQVRLGGDNLTLTEGEDISIRRVIIHPDYSASTAYNDIA 226
            ||..:|.:.:::|||||| .|.......||...:|    .....|::...||..|:..||.||||
Worm    66 CGATVIDDFWLVTAAHCALQLQTRSFVYVREPKNN----RERSFSVKEAYIHSGYNNQTADNDIA 126

  Fly   227 LLELET-AAKPELKPTCIWTQ-----KEVTNTLVTAIGYGQT---------SFAGLSSAQLLKVP 276
            ||.:.: .:|..:||.|:...     |:..|.:|  ||||.|         ......:.|...||
Worm   127 LLRISSDLSKLGIKPVCLVHDDSKLLKQYKNGVV--IGYGLTLGEDSSGEPKLINSQTLQSTSVP 189

  Fly   277 LKSVSNEECQHHYQ-KDQLAQGVLGTQMCAGDITGERDTCQGDSGGPLLMQDGLLGYV-VGITSL 339
            :  :|:::|...:: ...|:..:.|.|:|||...  ..|..||||||||:......|| :||||.
Worm   190 I--ISDDDCVKTWRFLSLLSVKITGYQICAGAYL--HGTAPGDSGGPLLIHKSNGEYVQIGITSY 250

  Fly   340 GQGCASGP------PSVYTRVSSFVDWIEGIVWPAQQVTNAPQPNQM-TSFSPEFDLRATI 393
            |.....|.      |.||||:|.:|.||:|::......::....:.: .:|.|.|.:..|:
Worm   251 GADGLDGVIDQGKFPGVYTRISKYVPWIQGVIGKTSMRSSVTSSSPIYFNFLPIFSIILTV 311

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
spirit	NP_001162707.1	CLIP	51..98	CDD:197829
		Tryp_SPc	132..364	CDD:238113	74/224 (33%)
		Tryp_SPc	132..361	CDD:214473	72/221 (33%)
try-3	NP_001367393.1	Tryp_SPc	38..279	CDD:238113	73/222 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010