DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment spirit and Gzmk

DIOPT Version :9

Sequence 1:	NP_001162707.1	Gene:	spirit / 31797	FlyBaseID:	FBgn0030051	Length:	393	Species:	Drosophila melanogaster
Sequence 2:	NP_032222.1	Gene:	Gzmk / 14945	MGIID:	1298232	Length:	263	Species:	Mus musculus

Alignment Length:	258	Identity:	78/258 - (30%)
Similarity:	127/258 - (49%)	Gaps:	34/258 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   128 FFVSVVGGMPTRPREFPFMAALGWRSNFDQRIYYRCGGALIANNFVLTAAHCADL--GGEPPSQV 190
            |...::||...:|...||||::.:||.      :.|||.||...:|||||||...  .|..|:.|
Mouse    22 FHTEIIGGREVQPHSRPFMASIQYRSK------HICGGVLIHPQWVLTAAHCYSWFPRGHSPTVV 80

  Fly   191 RLGGDNLTLTE--GEDISIRRVIIHPDYSASTAYNDIALLELETAAKPELKPTCIWTQ------- 246
             ||..:|:..|  .:...|::.|......:.:|.:||.|::|.|||  ||........
Mouse    81 -LGAHSLSKNEPMKQTFEIKKFIPFSRLQSGSASHDIMLIKLRTAA--ELNKNVQLLHLGSKNYL 142

  Fly   247 KEVTNTLVTAIGYGQTSFAGLSSAQLLK-VPLKSVSNEEC--QHHYQKDQLAQGVLGTQMCAGDI 308
            ::.|...||  |:|.|....|:::..|: |.:..:|.:.|  |.:|....:   :....:||||.
Mouse   143 RDGTKCQVT--GWGTTKPDLLTASDTLREVTVTIISRKRCNSQSYYNHKPV---ITKDMICAGDA 202

  Fly   309 TGERDTCQGDSGGPLLMQDGLLGYVVGITSLGQGCA-SGPPSVYTRVS-SFVDWIEGIVWPAQ 369
            .|::|:|:|||||||:.:    |....:.|.|..|. :..|.:||.:: .:..||:..:.|::
Mouse   203 RGQKDSCKGDSGGPLICK----GIFHALVSQGYKCGIAKKPGIYTLLTKKYQTWIKSKLAPSR 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
spirit	NP_001162707.1	CLIP	51..98	CDD:197829
		Tryp_SPc	132..364	CDD:238113	76/247 (31%)
		Tryp_SPc	132..361	CDD:214473	74/244 (30%)
Gzmk	NP_032222.1	Tryp_SPc	25..253	CDD:214473	74/245 (30%)
Gzmk	NP_032222.1	Tryp_SPc	26..256	CDD:238113	76/247 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D476534at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010