Protein Alignment spirit and TMPRSS11B

DIOPT Version :10

• Sequence 1: NP_572492.1
• Gene: spirit / 31797
• FlyBaseID: FBgn0030051
• Length: 393
• Species: Drosophila melanogaster
• Sequence 2: NP_872308.2
• Gene: TMPRSS11B / 132724
• HGNCID: 25398
• Length: 416
• Species: Homo sapiens
• Alignment Length: 280
• Identity: 84/280 - (30%)
• Similarity: 128/280 - (45%)
• Gaps: 53/280 - (18%)

  Fly    96 CCAPAVA-PIVTRSSQQACNELNKVSKVKEIDEFFVSVVGGMPTRPREFPFMAALGWRSNFDQRI 159
            ||...|| .|:|.         ||             :|.|..:....:|:.|::.|:..
Human   170 CCGRQVANSIITG---------NK-------------IVNGKSSLEGAWPWQASMQWKGR----- 207

  Fly   160 YYRCGGALIANNFVLTAAHC-ADLGGEPPSQVRLG--GDNLTLTEGEDISIRRVIIHPDYSASTA 221
             :.||.:||::.::|:|||| |.........|..|  .:...:|.    .::.:|.|.:||:...
Human   208 -HYCGASLISSRWLLSAAHCFAKKNNSKDWTVNFGIVVNKPYMTR----KVQNIIFHENYSSPGL 267

  Fly   222 YNDIALLEL--ETAAKPELKPTCIWTQK----EVTNTLVTAIG--YGQTSFAGLSSAQLLKVPLK 278
            ::||||::|  |.:....::..|:...|    |..|.:||..|  |...||..:.....||:
Human   268 HDDIALVQLAEEVSFTEYIRKICLPEAKMKLSENDNVVVTGWGTLYMNGSFPVILQEDFLKI--- 329

  Fly   279 SVSNEECQHHYQKDQLAQGVLGTQMCAGDITGERDTCQGDSGGPLLMQDGL-LGYVVGITSLGQG 342
             :.|:.|...|.....   |..|.:|||.::||.|.||.||||||...|.. :.::|||.|.|.|
Human   330 -IDNKICNASYAYSGF---VTDTMLCAGFMSGEADACQNDSGGPLAYPDSRNIWHLVGIVSWGDG 390

  Fly   343 CA-SGPPSVYTRVSSFVDWI 361
            |. ...|.|||||:|:.:||
Human   391 CGKKNKPGVYTRVTSYRNWI 410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spirit	NP_572492.1	CLIP	51..98	CDD:197829	1/1 (100%)
		Tryp_SPc	132..364	CDD:238113	76/243 (31%)
TMPRSS11B	NP_872308.2	SEA	45..142	CDD:460188
		Tryp_SPc	185..413	CDD:238113	76/243 (31%)