DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment spirit and CG43335

DIOPT Version :9

Sequence 1:	NP_001162707.1	Gene:	spirit / 31797	FlyBaseID:	FBgn0030051	Length:	393	Species:	Drosophila melanogaster
Sequence 2:	NP_001247121.1	Gene:	CG43335 / 12798413	FlyBaseID:	FBgn0263040	Length:	281	Species:	Drosophila melanogaster

Alignment Length:	259	Identity:	88/259 - (33%)
Similarity:	118/259 - (45%)	Gaps:	49/259 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   132 VVGGMPTRPREFPFMAALGWRSNFDQRIYYRCGGALIANNFVLTAAHCADLGGEPPSQVRLGGDN 196
            ::||........|:||.|      ....:|.|.|.||.|.||||||||.:  ......|||||..
  Fly    42 IIGGSDAEITSHPWMAYL------YNEFHYFCAGTLITNQFVLTAAHCIE--ASKNLTVRLGGSG 98

  Fly   197 LTLTEG-------EDISIRRVIIHPDYSASTAYNDIALLELETAAK--PELKPTCIWTQKEVTNT 252
            ||.::|       ||.|:...|.|..::.|...||||::.|....|  ..::|.||.....|...
  Fly    99 LTRSDGSMCQITAEDYSVSMAIKHKYFTPSIMLNDIAMIRLARTVKFYDHIRPICIILDPAVRLL 163

  Fly   253 LVTAIGYGQTSFA---GLSSAQ-----LLKVPLKSVSNEECQHHYQKDQLAQGVLGTQMCAGDIT 309
            |..    |.|..|   ||:..:     |.:.|:..::...|...|.. .:.||    |:||||
  Fly   164 LED----GMTLMATGWGLADKRMHPHLLQEAPITVMNRNVCSKLYDV-AITQG----QICAGD-- 217

  Fly   310 GERDTCQGDSGGPLLMQDGLLGYV-------VGITSLGQ-GCASGPPSVYTRVSSFVDWIEGIV 365
            .|.:||.|||||||   .|::.|.       .||||.|. .|.|  ||:||.:|::..||..:|
  Fly   218 KETNTCLGDSGGPL---GGVVNYYGDLRFVQYGITSFGDIECRS--PSIYTDLSTYSGWINMVV 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
spirit	NP_001162707.1	CLIP	51..98	CDD:197829
		Tryp_SPc	132..364	CDD:238113	87/256 (34%)
		Tryp_SPc	132..361	CDD:214473	85/253 (34%)
CG43335	NP_001247121.1	Tryp_SPc	41..272	CDD:214473	85/253 (34%)
CG43335	NP_001247121.1	Tryp_SPc	42..275	CDD:238113	87/256 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437442
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940