DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment spirit and CG43110

DIOPT Version :9

Sequence 1:	NP_001162707.1	Gene:	spirit / 31797	FlyBaseID:	FBgn0030051	Length:	393	Species:	Drosophila melanogaster
Sequence 2:	NP_001246396.1	Gene:	CG43110 / 12798330	FlyBaseID:	FBgn0262570	Length:	483	Species:	Drosophila melanogaster

Alignment Length:	245	Identity:	78/245 - (31%)
Similarity:	112/245 - (45%)	Gaps:	33/245 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   132 VVGGMPTRPREFPFMAALGWRSNFDQRIYYRCGGALIANNFVLTAAHCADLGGEPPSQ---VRLG 193
            ::.|.....:...:||.:     |: ..:..|||.:|..:||||.|||..      :|   ||||
  Fly    36 IISGSNASQQSAQYMAGI-----FN-TTHLLCGGTIIHEDFVLTVAHCKS------TQTLFVRLG 88

  Fly   194 GDNLTLTEGEDISIRRVIIHPDYSASTAYNDIALLELETAA--KPELKPTCIWTQKEVTNTL--V 254
            ..|:. ...:.|.:...|.||.||.||..|||||::||.:.  ...::|.||.....:...:  .
  Fly    89 AYNIN-HPTDQIRVIETIAHPQYSNSTYANDIALVKLERSVIFNLNIQPICIHLDATLGKQIRYY 152

  Fly   255 TAIGYGQTSFAGLSSAQLLKVPLKSVSNEECQHHYQKDQLAQGVLGTQMCAGDITGERDTCQGDS 319
            .|.|:|:|..|  ..:.:|:....:.:|....|.|    |.......|:||  .|.:.|||.|||
  Fly   153 NAFGWGRTRNA--EQSDILQRIFVNRTNPMICHLY----LGMSPDPKQICA--TTDQGDTCAGDS 209

  Fly   320 GGPLLMQDGLLG----YVVGITSLGQGCASGPPSVYTRVSSFVDWIEGIV 365
            ||||:.:....|    ...||||.|....:| ..:||.||.:..||..||
  Fly   210 GGPLISKITYQGKNFDTQFGITSYGTRECNG-VGLYTDVSQYSGWIANIV 258

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
spirit	NP_001162707.1	CLIP	51..98	CDD:197829
		Tryp_SPc	132..364	CDD:238113	76/242 (31%)
		Tryp_SPc	132..361	CDD:214473	74/239 (31%)
CG43110	NP_001246396.1	Tryp_SPc	35..254	CDD:214473	74/239 (31%)
CG43110	NP_001246396.1	Tryp_SPc	36..257	CDD:238113	76/242 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437518
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940