DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG32305 and CYR1

DIOPT Version :9

Sequence 1:NP_728725.2 Gene:CG32305 / 317967 FlyBaseID:FBgn0052305 Length:1164 Species:Drosophila melanogaster
Sequence 2:NP_012529.3 Gene:CYR1 / 853452 SGDID:S000003542 Length:2026 Species:Saccharomyces cerevisiae


Alignment Length:562 Identity:120/562 - (21%)
Similarity:209/562 - (37%) Gaps:169/562 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly   132 LGTIYSGAAYPTVPC--------------YDHVVLVSVYMTL-PIAFYQGSSVYVLGMVVSIIYI 181
            |..::....:|..|.              :.||.|.::.:|. ||.|||.:| .:..:.||    
Yeast   765 LSFVFKFLFHPVTPSHFTPEQEQRIMRSEFVHVDLRNMDLTTPPIIFYQHTS-EIESLDVS---- 824

  Fly   182 GYAFYMQYLNDQVSFYLLASY---AIYLFTLNLIFSFFTIIRDYGLRRAILSRYQLVYQNIVYQL 243
                      :..:.:|...:   :|.|.:|.::     .||.......|...|:||...:....
Yeast   825 ----------NNANIFLPLEFIESSIKLLSLRMV-----NIRASKFPSNITKAYKLVSLELQRNF 874

  Fly   244 VMKKENGLLESILPRKMIRTLQEEICSRIEDQDKNFTPSKAGLRKLFLEP-----YPNV-----S 298
            :.|..|.:::  |....|..||   |:.:|.....|...| .|:.|.|..     ||.|     :
Yeast   875 IRKVPNSIMK--LSNLTILNLQ---CNELESLPAGFVELK-NLQLLDLSSNKFMHYPEVINYCTN 933

  Fly   299 ILVADMVNYTHLTTTLEAPQLVEILHDLFVNFDLAANRNRAMRIKFLGD------------SYNC 351
            :|..|: :|..:.:   .||..:.|..| ...:|:.|     ::.|:||            .||.
Yeast   934 LLQIDL-SYNKIQS---LPQSTKYLVKL-AKMNLSHN-----KLNFIGDLSEMTDLRTLNLRYNR 988

  Fly   352 VAGIPNYFPAHASCCVDQALEMIHITQG-VSSRRELDINLR-IGVHSGEVFAGIIGHTKWQF-DI 413
            ::.|    ..:||     .|:.:.:|.. :|:..:....|| :.:....:       |...| |.
Yeast   989 ISSI----KTNAS-----NLQNLFLTDNRISNFEDTLPKLRALEIQENPI-------TSISFKDF 1037

  Fly   414 WSKDV-DIT-NRLESSGLPG----------LVHVSQRTLSMLDEH------YIFREGTEAAKN-- 458
            :.|:: .:| |:.:.|.:||          .:.::|..|:.|.:.      .:|   ...|:|  
Yeast  1038 YPKNMTSLTLNKAQLSSIPGELLTKLSFLEKLELNQNNLTRLPQEISKLTKLVF---LSVARNKL 1099

  Fly   459 ---DPILQQ-AGIRTF-LVSNRLPDAVEPGELDDELSSASINS-------------CRLSYGGYY 505
               .|.|.| ..:||. |.||.:.|.|: |..:.||:|.:|:|             ..:|||.  
Yeast  1100 EYIPPELSQLKSLRTLDLHSNNIRDFVD-GMENLELTSLNISSNAFGNSSLENSFYHNMSYGS-- 1161

  Fly   506 EEIQIKAQREIMKEV-------DQM-AVGHCFI----------EWRRSSSMKKQDFNEEYLFSNQ 552
                 |..:.:|..:       |.| .:.:||:          .:...|.||.:...|.||..|:
Yeast  1162 -----KLSKSLMFFIAADNQFDDAMWPLFNCFVNLKVLNLSYNNFSDVSHMKLESITELYLSGNK 1221

  Fly   553 IHLVLG-VFRSWKREWEFHNLPDLMIKYTMLLVLCAGLAIMS 593
            :..:.| ....|.      :|..||:....:|.|.|.|:.:|
Yeast  1222 LTTLSGDTVLKWS------SLKTLMLNSNQMLSLPAELSNLS 1257

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG32305NP_728725.2 CYCc 251..449 CDD:214485 48/240 (20%)
Nucleotidyl_cyc_III 292..445 CDD:299850 37/189 (20%)
CYCc 814..1056 CDD:214485
Nucleotidyl_cyc_III 845..1081 CDD:299850
CYR1NP_012529.3 Ad_cyc_g-alpha 368..418 CDD:369912
RA_PHLPP_like 678..776 CDD:340473 1/10 (10%)
PLN00113 792..>1273 CDD:215061 117/535 (22%)
leucine-rich repeat 796..817 CDD:275380 10/21 (48%)
leucine-rich repeat 818..839 CDD:275380 3/34 (9%)
leucine-rich repeat 840..864 CDD:275380 6/28 (21%)
leucine-rich repeat 865..887 CDD:275380 5/23 (22%)
leucine-rich repeat 888..910 CDD:275380 7/25 (28%)
leucine-rich repeat 911..933 CDD:275380 6/21 (29%)
leucine-rich repeat 934..956 CDD:275380 6/25 (24%)
leucine-rich repeat 957..978 CDD:275380 6/26 (23%)
leucine-rich repeat 979..1018 CDD:275380 8/47 (17%)
leucine-rich repeat 1019..1041 CDD:275380 5/28 (18%)
leucine-rich repeat 1042..1065 CDD:275380 5/22 (23%)
leucine-rich repeat 1066..1088 CDD:275380 3/21 (14%)
leucine-rich repeat 1089..1111 CDD:275380 6/24 (25%)
leucine-rich repeat 1167..1187 CDD:275380 3/19 (16%)
leucine-rich repeat 1191..1211 CDD:275380 3/19 (16%)
leucine-rich repeat 1236..1258 CDD:275380 8/22 (36%)
leucine-rich repeat 1259..1287 CDD:275380
PP2C 1374..1617 CDD:395385
CYCc 1613..1825 CDD:214485
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG2114
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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