DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG32305 and Phlpp1

DIOPT Version :9

Sequence 1:NP_728725.2 Gene:CG32305 / 317967 FlyBaseID:FBgn0052305 Length:1164 Species:Drosophila melanogaster
Sequence 2:XP_038946976.1 Gene:Phlpp1 / 59265 RGDID:621308 Length:1718 Species:Rattus norvegicus


Alignment Length:416 Identity:81/416 - (19%)
Similarity:143/416 - (34%) Gaps:132/416 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   300 LVADMVNYTHLTTTLEAP------------QLVEILH---DLFVNFD--------LAANRNRAMR 341
            |:.|.|::....|.|:..            ..:|:||   :..|..:        |.|:.|..::
  Rat   785 LITDEVDFLQHVTQLDLRDNKLGDLDAMIFNNIEVLHCERNQLVTLNICGYFLKALYASSNELVQ 849

  Fly   342 ---------IKFLGDSYNCVAGIPNYFPAHASCCVDQALEMIHITQGVSSRRELDINLRIGVHSG 397
                     :.::..|.||:..:|.:      .|..:.||::.|  |.:...||...|.......
  Rat   850 LDVYPVPNYLSYMDVSRNCLESVPEW------VCESRKLEVLDI--GHNQICELPARLFCNSSLR 906

  Fly   398 EVFAGIIGHTKWQFDIWSKDVDITNRLESSGLPGLVHVSQRTLSMLDEHYIFREGTEAAKNDPIL 462
            ::.|   ||               |||  :.||  ..:.:.::.:||..:  .:..|...|  :|
  Rat   907 KLLA---GH---------------NRL--ARLP--ERLERTSVEVLDVQH--NQIIELPPN--LL 945

  Fly   463 QQAGIRTFL--VSNRLPDAVEPGELDDELSS----------ASINSCRLSYGGY---------YE 506
            .:|....||  .:|:| :.:.|..|.:|.||          :..:.|.....|:         |.
  Rat   946 MKADSLRFLNASANKL-ETLPPATLSEETSSILQELYLTNNSLTDKCVPLLTGHPRLKILHMAYN 1009

  Fly   507 EIQI-----KAQREIMKEVDQMAVGHCFIEWRRSSSMKKQDFNEEYLFSNQIHLVLG------VF 560
            .:|.     .|:.|.::|:|             .|..|.:......:...::|.|:.      ||
  Rat  1010 RLQSFPASKMAKLEELEEID-------------ISGNKLKAIPTTIMNCRRMHTVIAHSNCIEVF 1061

  Fly   561 RSWKREWEFHNLPDL--------MIKYTMLLVLCAGLAIMSINLIEEATYPDILVLLGILLILLI 617
            .      |...||::        :.:.:.|..|......:|.|.:.|.|.|:.|.      ..|.
  Rat  1062 P------EVMQLPEVKSTEGNGSLSRSSFLFPLFHQCVDLSCNELSEITLPENLP------PKLQ 1114

  Fly   618 LCILAGYKKLRLQWKKLTPMSQPSCF 643
            ...|.|..:|.|..|.|..::...||
  Rat  1115 ELDLTGNPRLALDHKSLELLNNIRCF 1140

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG32305NP_728725.2 CYCc 251..449 CDD:214485 34/180 (19%)
Nucleotidyl_cyc_III 292..445 CDD:299850 33/176 (19%)
CYCc 814..1056 CDD:214485
Nucleotidyl_cyc_III 845..1081 CDD:299850
Phlpp1XP_038946976.1 Ubiquitin_like_fold 176..>224 CDD:421700
PHA03247 <237..443 CDD:223021
RA_PHLPP1 <424..491 CDD:340760
PH_PHLPP-like 498..594 CDD:270131
PLN00113 602..>1109 CDD:215061 71/377 (19%)
leucine-rich repeat 604..624 CDD:275380
leucine-rich repeat 625..655 CDD:275380
leucine-rich repeat 679..701 CDD:275380
leucine-rich repeat 702..724 CDD:275380
leucine-rich repeat 725..771 CDD:275380
leucine-rich repeat 772..795 CDD:275380 3/9 (33%)
leucine-rich repeat 796..816 CDD:275380 2/19 (11%)
leucine-rich repeat 817..858 CDD:275380 7/40 (18%)
leucine-rich repeat 859..881 CDD:275380 5/27 (19%)
leucine-rich repeat 882..904 CDD:275380 7/23 (30%)
leucine-rich repeat 905..926 CDD:275380 8/42 (19%)
leucine-rich repeat 927..950 CDD:275380 6/26 (23%)
leucine-rich repeat 951..974 CDD:275380 7/23 (30%)
leucine-rich repeat 977..1000 CDD:275380 2/22 (9%)
leucine-rich repeat 1001..1024 CDD:275380 3/22 (14%)
leucine-rich repeat 1067..1112 CDD:275380 10/50 (20%)
PP2Cc 1151..1403 CDD:214625
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG2114
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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