Protein Alignment CG32305 and si:ch211-132f19.7

DIOPT Version :9

• Sequence 1: NP_728725.2
• Gene: CG32305 / 317967
• FlyBaseID: FBgn0052305
• Length: 1164
• Species: Drosophila melanogaster
• Sequence 2: XP_688903.4
• Gene: si:ch211-132f19.7 / 560410
• ZFINID: ZDB-GENE-130530-619
• Length: 1183
• Species: Danio rerio
• Alignment Length: 1147
• Identity: 318/1147 - (27%)
• Similarity: 512/1147 - (44%)
• Gaps: 221/1147 - (19%)

  Fly    19 STVKDLEWRHLKNK-----CQNLRLELACSRLRELALMSNVVQIIWHVELLMVAHVILL-LALVK 77
            |||:.:....|.:|     .::|..:.:..:.|...:::||      :::|...|:|.: |||..
Zfish   120 STVRGIFLPALHHKFKSHDLEHLYQQHSSGQRRTSLVVTNV------IDILTKLHIIFIYLALAP 178

  Fly    78 DII----------LVTMVPYFAVM------LFSPFIMLLSMQNNVGMITNTLISWLMALFLTSMD 126
            :::          |:.:.....|:      |.||..:..:          .|.|||       ..
Zfish   179 EMVDSQHGWLAGLLMALGAIICVLVLTCKGLMSPDYLRYA----------GLASWL-------SQ 226

  Fly   127 LVSDLLGTIYSGAAYPTVPCYDHVVLVSVYMTLPIAFYQGSSVYVLGMVVSIIYIGYAFYMQYLN 191
            .|..|.|.:|  ........|....|.::|..||:.....   ..:|.:.:.:::....:..|.:
Zfish   227 TVQALGGLVY--GLETDQSWYVLFTLFAIYTLLPLPLLWS---ICMGFLTAALHLFVDTFKNYND 286

  Fly   192 DQVSFYLLASYAIYLFTLNLIFSFFTIIRDYGLRRAILSRYQLVYQNIVYQLVMKKENGLLESIL 256
            ..:...|||...:|: .:|....|...:.|...|:|.|...:.:...:..:...:::..|:.|||
Zfish   287 TAIVRKLLAKGLLYM-GMNTAGLFIHYLSDRAQRQAFLETRRCIEGRVKMERENQRQERLVMSIL 350

  Fly   257 PRKMIRTLQEEICSRIEDQDKNFTPSKAGLRKLFLEPYPNVSILVADMVNYTHLTTTLEAPQLVE 321
            |    |.:..|:...:...|....|.:  ..|.:...|.:||||.||:..:|.|:.|:.|.:||.
Zfish   351 P----RFIAMEMIGDMTALDDELLPQQ--FHKTYFHQYKDVSILFADIKGFTSLSMTMPAQELVR 409

  Fly   322 ILHDLFVNFDLAANRNRAMRIKFLGDSYNCVAGIPNYFPAHASCCVDQALEMIHITQGVSSRREL 386
            .|::||..||..|..|..||||.|||.|.||:|:|....|||.|||:..|.||:..:.|....:.
Zfish   410 TLNELFGRFDRLAEENHCMRIKILGDCYYCVSGVPEPQTAHARCCVEMGLAMINTIRYVRKELKR 474

  Fly   387 DINLRIGVHSGEVFAGIIGHTKWQFDIWSKDVDITNRLESSGLPGLVHVSQRTLSMLDEHYIFRE 451
            |:::|||:|||.|..|::|..|||||:||.|||:.|.||:.|:||.:|:|:.||..|:..|...|
Zfish   475 DMDMRIGIHSGSVLCGVLGLQKWQFDVWSWDVDVANMLEAGGIPGRIHISRATLDCLEGVYETEE 539

  Fly   452 GTEAAKNDPILQQAGIRTFLVSNRLPDAVEPGEL-----DDELSSASI-------NSCRLSYGGY 504
            |....:|: .|::..|.|||:.:...|..||.::     |:...||.:       .:|.|:....
Zfish   540 GRGHERNE-FLRKHKIDTFLIRHTPQDDKEPPKVRRTSKDETTWSAELPFDNIIGMNCILATFTN 603

  Fly   505 YEEIQIKAQ--------REIMKEVDQMAVGHCFIEWRRSSSMKKQDFNEEYLFSNQIHLVLGVFR 561
            ...:.:..|        |||.|.:.|.      ||.|.|..|:|:......|          ||:
Zfish   604 GSLVHLPNQITPHCAGSREINKRIKQA------IEVRSSERMRKEHITPFTL----------VFK 652

  Fly   562 SWKREWEFHNLPDLMIK------YTMLLVLCAGLAIMSINLIEEATYPDILVLLGILLILLILCI 620
            ....|.:|..:.|.|.|      :.:||.:.|..|::.    ....:|.|:..|..|.:.:::.:
Zfish   653 DTHIEGKFSQMRDEMFKSNLACSFLLLLFIMAAQALIP----SPQFFPMIIQFLVFLFVYMLVLL 713

  Fly   621 LAGYKKLRLQWKKLTPMSQPSCFLSRWLLRISERIEDSLFVRIPLTMVVLLLLYVMSSQAVFSCD 685
            :.    |..::|:..|..|..|.   |       |.::..:|..||:..:.:.:.::|..:|.|:
Zfish   714 VT----LAEEFKRSPPYLQHLCC---W-------IHETKSIRNLLTLTAIAINFGVASCNIFWCN 764

  Fly   686 VAKLELSIIEAHLYNEKS--YAECFGPWTVTYC-----------VVIVISLLFVVPGCPLVIKIL 737
            ....|         .|||  .:|....|.|..|           |.:|...:|:...|.|.:.:|
Zfish   765 GTFEE---------TEKSNKNSEHGKQWPVNICTHPEFFVLSGVVAMVTCAVFLRLSCLLKLAVL 820

  Fly   738 AGLLILGLHLGTVHLYYGFAFERSETTDLGLKSDYAH----TWYLVALFIVLVL-RERHVNYLRK 797
            .  |::.::...:.:.:...|.|........:|.|..    :..|:|:|:|:|| ..|.:....:
Zfish   821 T--LVIAVYTYLIEVAFHVLFIRQHQNSQIQRSQYLRRKGISVLLMAMFVVVVLYNSRQLETTSR 883

  Fly   798 FNYFMRVCYEEAHQQTDE--KLRS-IKIIMANILPTHVAQVYKVR-RPHDQLYYENFSKVAVMFA 858
            .::..|:   :|.|:.::  :||. .:.::.||||.|||:.:..| |.::.|:.|::.:|.||||
Zfish   884 LDFLWRL---QARQEVEDMKELREHNECLLYNILPAHVARHFLERDRNNEDLFSESYERVGVMFA 945

  Fly   859 SIENF----------NADTAGLRILHEIICCFDDLLVDYQTRYKIEKIKVMGWTYMVACGLETDH 913
            ||..|          :.|...||:|:|||..||:|| |......|||||.:|..||.|.||.
Zfish   946 SIPGFSDYYEKKELIHQDVECLRLLNEIIADFDELL-DEPYFQDIEKIKTIGSCYMAASGLS--- 1006

  Fly   914 YTDFSIDIPVKQPEADSEIRRGSSVLTVHFGSTEDDEMSGDNVSQPYAQVQDVAVLVMTEFALDL 978
                    |.||                   ..||:          :|.   ::.||:  |||.:
Zfish  1007 --------PEKQ-------------------ECEDE----------WAH---LSTLVL--FALAM 1029

  Fly   979 LRIMHDIRYNYVFSEYDTFLTGSLKIGISHGSVMAGVVGLSKPHYDIWGHTVNMASRMSSTGLLD 1043
            ...:.:|...   :..|.:    |::|||||.|:|||:|.:||.|||||.|||:||||.||||..
Zfish  1030 QETLKEINKR---TSNDFW----LRVGISHGPVVAGVIGATKPQYDIWGMTVNLASRMDSTGLSG 1087

  Fly  1044 NIQVTRHTAKVLRQFNIRCNYRGHTEVKGV----GKVPTYLV 1081
            .|||...|::||.:.......||...||||    |.|.||.|
Zfish  1088 RIQVPEATSRVLAEHGFMLQLRGEIYVKGVSERRGAVRTYFV 1129

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32305	NP_728725.2	CYCc	251..449	CDD:214485	84/197 (43%)
		Nucleotidyl_cyc_III	292..445	CDD:299850	73/152 (48%)
		CYCc	814..1056	CDD:214485	91/255 (36%)
		Nucleotidyl_cyc_III	845..1081	CDD:299850	91/249 (37%)
si:ch211-132f19.7	XP_688903.4	AC_N	<133..375	CDD:292831	50/276 (18%)
		CYCc	338..537	CDD:214485	84/204 (41%)
		Guanylate_cyc	381..559	CDD:278633	81/178 (46%)
		DUF1053	579..667	CDD:283888	22/103 (21%)
		CYCc	903..1103	CDD:214485	91/252 (36%)
		Guanylate_cyc	932..1131	CDD:278633	92/251 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810