Protein Alignment CG32305 and gucy1a1

DIOPT Version :9

• Sequence 1: NP_728725.2
• Gene: CG32305 / 317967
• FlyBaseID: FBgn0052305
• Length: 1164
• Species: Drosophila melanogaster
• Sequence 2: NP_001296458.1
• Gene: gucy1a1 / 550420
• ZFINID: ZDB-GENE-050417-230
• Length: 679
• Species: Danio rerio
• Alignment Length: 522
• Identity: 113/522 - (21%)
• Similarity: 205/522 - (39%)
• Gaps: 126/522 - (24%)

  Fly    62 ELLMVAHVILLLALVKDIILVTMVPYFAVMLFSPFIMLLSMQNNVGMITNTLISWLMALFLTSMD 126
            |:....|...:|.|.||..|:|:  ||    |:|      :.:.....:..:.:....|:.|.::
Zfish   181 EIQRYIHQASILCLDKDPGLLTV--YF----FNP------LPSTELFFSGIIQAAACLLYCTRVE 233

  Fly   127 LVSDLLG-------------TIYS-----GAAYPTVPCYDH----VVLVSVYMTLPIAFYQGSSV 169
            :..|:.|             .:||     |.:....|...|    :.|..:|.|.|...
Zfish   234 VRMDVGGKDSGALQADHQPHLLYSVVVRDGRSLTPSPMRTHTSGDIPLSLLYSTFPFHI------ 292

  Fly   170 YVLGMVVSIIYIGYAFYMQY-----------LNDQ---VSFYLLASYAIYLFTLNLIFSFFTIIR 220
             :|...:.::.||.....:.           .|:.   ||..:.||:...|..||.  .|...::
Zfish   293 -LLDQEMGLLQIGDGLRRRLGRCRDGQRRPAFNEHFAIVSPEIRASFQDILTMLNT--QFLLRVK 354

  Fly   221 DYGLRRA------ILSRYQLVYQNIVYQL-------VMKKE----NGLLESILPRKMIRTLQEEI 268
            .:|...|      :..:.|:::.:.:..|       |.|.|    .||..|.:|  :...|::.:
Zfish   355 QHGASSADSPGKHMDLKGQMIFMSEMSALLFLGSPCVDKLEELTGRGLYLSDIP--IHNALRDVV 417

  Fly   269 C--SRIEDQD---KNFTPSKAGLRK---------------LF------------------LEPYP 295
            .  .:.:.||   |....:||.|.:               ||                  .:.:.
Zfish   418 LVGEQTKAQDGLKKRLGKAKAALEQAHQALEEEKRRTVELLFTIFPGNVAQRLWQGLPVQAKKFD 482

  Fly   296 NVSILVADMVNYTHLTTTLEAPQLVEILHDLFVNFDLAANRNRAMRIKFLGDSYNCVA-GIPNYF 359
            :|::|.:|:|.:|.:.:.....|:|.:|.:|:..||.........:::.:||:| ||| |:....
Zfish   483 HVTVLFSDIVGFTAICSRCTPMQVVNMLSELYTRFDHHCGELDVYKVETIGDAY-CVAGGLHKES 546

  Fly   360 PAHASCCVDQALEMIHITQGVSSRRELDINLRIGVHSGEVFAGIIGHTKWQFDIWSKDVDITNRL 424
            |.||......||:|:.::..|::.....|.:|||:|||.|.||::|....::.::..:|.:.|:.
Zfish   547 PTHAVQIALMALKMMELSDEVTTPMGEVIRMRIGIHSGSVLAGVVGVKMPRYCLFGNNVTLANKF 611

  Fly   425 ESSGLPGLVHVSQRTLSMLDE----HYIFREGTEAAKNDPILQQAGIRTFL-----VSNRLPDAV 480
            ||..||..::||..|..:|.:    ..|.|...:...|.| ....|:..||     .:|..|:..
Zfish   612 ESCSLPRKINVSPTTYRLLKDCPEFTLIPRTREDLPPNFP-TDIPGVCYFLQAHDQKTNAAPEET 675

  Fly   481 EP 482
            :|
Zfish   676 QP 677

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32305	NP_728725.2	CYCc	251..449	CDD:214485	58/240 (24%)
		Nucleotidyl_cyc_III	292..445	CDD:299850	46/153 (30%)
		CYCc	814..1056	CDD:214485
		Nucleotidyl_cyc_III	845..1081	CDD:299850
gucy1a1	NP_001296458.1	HNOBA	279..470	CDD:285003	36/201 (18%)
		CYCc	449..635	CDD:214485	48/186 (26%)
		Guanylate_cyc	476..647	CDD:278633	48/171 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900