DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32305 and CG31183

DIOPT Version :9

Sequence 1:	NP_728725.2	Gene:	CG32305 / 317967	FlyBaseID:	FBgn0052305	Length:	1164	Species:	Drosophila melanogaster
Sequence 2:	NP_001287342.1	Gene:	CG31183 / 41927	FlyBaseID:	FBgn0051183	Length:	1417	Species:	Drosophila melanogaster

Alignment Length:	297	Identity:	78/297 - (26%)
Similarity:	125/297 - (42%)	Gaps:	72/297 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   793 NYLRKFNYF---MRVCYEEAHQQTDEKLRSIKIIMANILPTHVAQVYKVRRPHDQLYYENFSKVA 854
            |.|::...:   :....||..|...|:.:..:.::..:||..||......:|   :..|.|.:|.
  Fly   892 NLLKRMELYANNLEELVEERTQDYHEEKKKCEKLLYQLLPQSVAAQLISGQP---VVAETFDQVT 953

  Fly   855 VMFASIENFNADTAG------LRILHEIICCFDDLLVDYQTRYKIEKIKVMGWTYMVACGLETDH 913
            :.|:.|..|.|.:|.      ::.|:::..|||.::.::.. ||:|.|   |..|||..||
  Fly   954 IYFSDIVGFTAISAESTPMQVVQFLNDLYTCFDSIVENFDV-YKVETI---GDAYMVVSGL---- 1010

  Fly   914 YTDFSIDIPVKQPEADSEIRRGSSVLTVHFGSTEDDEMSGDNVSQPYAQVQDVAVLVMTEFALDL 978
                             .||.|:.                        ..:::|.|     ||.|
  Fly  1011 -----------------PIRNGNQ------------------------HAREIARL-----ALAL 1029

  Fly   979 LRIMHDIRYNYVFSEYDTFLTGSLKIGISHGSVMAGVVGLSKPHYDIWGHTVNMASRMSSTGLLD 1043
            |..:|:.|.::  ...|..   .|:||:..|:.:||||||..|.|.::|.|||.||||.|.|...
  Fly  1030 LEAVHNFRIHH--RPEDRL---KLRIGLHTGACVAGVVGLKMPRYCLFGDTVNTASRMESNGEAL 1089

  Fly  1044 NIQVTRHTAKVLRQF-NIRCNYRGHTEVKGVGKVPTY 1079
            .|.::..|.:.|.:| ......||...:||.|::.||
  Fly  1090 KIHISETTKEALDEFGTFVTTRRGFVPMKGKGEMLTY 1126

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32305	NP_728725.2	CYCc	251..449	CDD:214485
		Nucleotidyl_cyc_III	292..445	CDD:299850
		CYCc	814..1056	CDD:214485	64/247 (26%)
		Nucleotidyl_cyc_III	845..1081	CDD:299850	67/242 (28%)
CG31183	NP_001287342.1	PBP1_NPR_like	88..498	CDD:107368
		ANF_receptor	108..473	CDD:279440
		PK_GC-A_B	589..883	CDD:270944
		Pkinase_Tyr	613..877	CDD:285015
		HNOBA	<893..938	CDD:285003	9/44 (20%)
		CYCc	917..1108	CDD:214485	66/252 (26%)
		Guanylate_cyc	944..1130	CDD:278633	67/242 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453936
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740