DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32305 and Gyc88E

DIOPT Version :9

Sequence 1:	NP_728725.2	Gene:	CG32305 / 317967	FlyBaseID:	FBgn0052305	Length:	1164	Species:	Drosophila melanogaster
Sequence 2:	NP_001036711.1	Gene:	Gyc88E / 41825	FlyBaseID:	FBgn0038295	Length:	1097	Species:	Drosophila melanogaster

Alignment Length:	504	Identity:	120/504 - (23%)
Similarity:	216/504 - (42%)	Gaps:	86/504 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 YRSLSTVKDLEWRHLKNKCQNLRLELACSRLRELALMSNVVQIIWHVELLMV----AHVILLLAL 75
            |.::..::::. |:..:|  .:.:||    :||..|...|     ||...:.    |..:..||:
  Fly   142 YYTMGQIREVA-RYFYHK--EMHIEL----VREEILFDTV-----HVTFQLTFDNRAFTLASLAM 194

  Fly    76 VKDIILVTMVPYFAVMLFS--PFIMLLSMQNNVGMITNTLISWLMALF---LTS-MDLVSDLLGT 134
            .::   ...:|..|.:||.  ||.|:......|..|.|:|:..|..|.   :|: .|||..|:..
  Fly   195 TRE---EKHLPISAHVLFEIFPFCMVFGADMVVRSIGNSLMVILPELLGKKITAWFDLVRPLIAF 256

  Fly   135 IYSGAAYPTVPCYDHVVLVSVYMTLPI------AFYQGS----SVYVLGMVV------SIIYIGY 183
            .:......|...::.|.:..|.....:      ....||    |:.:.|.:|      .|:::|
  Fly   257 KFQTILNRTNNIFELVTVDPVTERFDVQNEDLLQHEDGSEPEKSLRLKGQMVYMENWRMIMFLG- 320

  Fly   184 AFYMQYLNDQVSFYLLASYAIYLFTLNLIFSFFTIIRDYGLRRAILSRYQLVYQNIVYQLVMKKE 248
               ...:.|..|   |.:..:|:..|::        .|:.....:....|.|...:......:|.
  Fly   321 ---TPVMPDLTS---LITTGLYINDLSM--------HDFSRDLMLAGTQQSVELKLALDQEQQKS 371

  Fly   249 NGLLES--ILPRKMIRT---LQEEICSRIEDQDKNFTPSKAGLRK-----LFLEPYPNVSILVAD 303
            ..|.||  :|..:|.||   |.:.|..::.|:          ||:     ...|.:.:||||.:|
  Fly   372 KKLEESMRLLDEEMRRTDELLYQMIPKQVADR----------LRRGENPIDTCEMFDSVSILFSD 426

  Fly   304 MVNYTHLTTTLEAPQLVEILHDLFVNFDLAANRNRAMRIKFLGDSYNCVAGIPNYFPAHASCCVD 368
            :|.:|.:.:.:...::|.:|:.::..||....||...:::.:||:|..|||.|:....||....|
  Fly   427 IVTFTEICSRITPMEVVSMLNAMYSIFDKLTERNSVYKVETIGDAYMVVAGAPDKDANHAERVCD 491

  Fly   369 QALEMIH-ITQGVSSRRELDINLRIGVHSGEVFAGIIGHTKWQFDIWSKDVDITNRLESSGLPGL 432
            .||:|:. ||..........:.:|:|||||.|.|||:|....::.::...|:..:|:||:.:...
  Fly   492 MALDMVDAITDLKDPSTGQHLRIRVGVHSGAVVAGIVGLKMPRYCLFGDTVNTASRMESTSIAMK 556

  Fly   433 VHVSQRTLSMLDEHY-IFREGTEAAKNDPILQQAGIRTFLV---SNRLP 477
            ||:|:.|..::..:| |...|....|.     :..:.|:.:   .||||
  Fly   557 VHISESTKVLIGPNYKIIERGEIDVKG-----KGTMGTYWLEERENRLP 600

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32305	NP_728725.2	CYCc	251..449	CDD:214485	61/209 (29%)
		Nucleotidyl_cyc_III	292..445	CDD:299850	48/153 (31%)
		CYCc	814..1056	CDD:214485
		Nucleotidyl_cyc_III	845..1081	CDD:299850
Gyc88E	NP_001036711.1	HNOB	2..164	CDD:311572	3/24 (13%)
		HNOBA	201..404	CDD:311573	47/227 (21%)
		CYCc	383..571	CDD:214485	56/197 (28%)
		Herpes_ICP4_C	794..>955	CDD:332854
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453930
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740