DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32305 and CG10738

DIOPT Version :9

Sequence 1:	NP_728725.2	Gene:	CG32305 / 317967	FlyBaseID:	FBgn0052305	Length:	1164	Species:	Drosophila melanogaster
Sequence 2:	NP_729905.2	Gene:	CG10738 / 39516	FlyBaseID:	FBgn0036368	Length:	1250	Species:	Drosophila melanogaster

Alignment Length:	394	Identity:	102/394 - (25%)
Similarity:	155/394 - (39%)	Gaps:	99/394 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   223 GLRRAILSRYQLV---YQNIVYQLV----------MKKENGLLESILPRKMIRTLQEEICSRIED 274
            |:|..|......:   |.|.:..||          .||.:.||..:|||          |  :.|
  Fly   853 GMRPNIFDNMMAMMEKYANNLEALVDDRTDQLQEEKKKTDALLHEMLPR----------C--VAD 905

  Fly   275 QDKNFTPSKAGLRKLFLEPYPNVSILVADMVNYTHLTTTLEAPQLVEILHDLFVNFDLAANRNRA 339
            |      .|.| .|:..|.|..|||..:|:|.:|.::......|:|:.|:||:..||........
  Fly   906 Q------LKKG-HKVDPEHYEQVSIYFSDIVGFTAMSAECTPLQVVDFLNDLYTCFDSIIGHYDV 963

  Fly   340 MRIKFLGDSYNCVAGIP-NYFPAHASCCVDQALEMIHITQGVSS-----RRELDINLRIGVHSGE 398
            .:::.:||:|..|:|:| .....||:   :.|...:|:...||.     |....:.||||:|||.
  Fly   964 YKVETIGDAYMVVSGLPLRNGDLHAA---EIATMSLHLLSAVSEFKIRHRPTNRLLLRIGIHSGP 1025

  Fly   399 VFAGIIGHTKWQFDIWSKDVDITNRLESSGLPGLVHVSQRTLSMLDE------------------ 445
            |.||::|....::.::...|:..:|:||||:|..:|.|.:...:||.
  Fly  1026 VCAGVVGLKMPRYCLFGDTVNTASRMESSGVPLKIHCSWQCRQLLDRLGGYHFAERGVISMKGKG 1090

  Fly   446 ----HYIFREGTEA---------------AKNDPI---LQQA-------GIRTFLVSNRLPDAVE 481
                :::..|..||               |.|..|   ::||       |||:.|....||
  Fly  1091 DQRTYWLLGEDEEARTRRTYERSQRRGSRALNKFIQGTIKQAQEQANEYGIRSSLKQKNLP---- 1151

  Fly   482 PGELDDELSSASINSCRLSYGGYYEEIQIKAQREIMKEVDQMAVGHCFIEWRRSSSMKKQDFNEE 546
            ...|....|..|....|.:.|...|..:..:. |.:.|||.      :...||||....|...||
  Fly  1152 RNSLTRSSSLESPKKLRFAAGSLLEHHRYHSD-EALLEVDS------YTGLRRSSGGSTQSRYEE 1209

  Fly   547 YLFS 550
            ...|
  Fly  1210 TTLS 1213

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32305	NP_728725.2	CYCc	251..449	CDD:214485	61/225 (27%)
		Nucleotidyl_cyc_III	292..445	CDD:299850	49/158 (31%)
		CYCc	814..1056	CDD:214485
		Nucleotidyl_cyc_III	845..1081	CDD:299850
CG10738	NP_729905.2	PBP1_Speract_GC_like	41..441	CDD:107365
		ANF_receptor	67..416	CDD:279440
		PK_GC-A_B	570..853	CDD:270944	102/394 (26%)
		TyrKc	597..847	CDD:197581
		HNOBA	<862..907	CDD:285003	14/62 (23%)
		CYCc	886..1078	CDD:214485	63/213 (30%)
		Guanylate_cyc	913..1099	CDD:278633	50/188 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810