DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32305 and gcy-9

DIOPT Version :9

Sequence 1:	NP_728725.2	Gene:	CG32305 / 317967	FlyBaseID:	FBgn0052305	Length:	1164	Species:	Drosophila melanogaster
Sequence 2:	NP_509897.3	Gene:	gcy-9 / 191645	WormBaseID:	WBGene00001536	Length:	1081	Species:	Caenorhabditis elegans

Alignment Length:	283	Identity:	81/283 - (28%)
Similarity:	122/283 - (43%)	Gaps:	81/283 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   807 EEAHQQTDEKLRSIKIIMANILPTHVAQVYKVRRP-HDQLYYENFSKVAVMFASIENF---NADT 867
            |||.:|.|..|.|       :||..:|:..|:.:| ..|||    |...|:|:.|..|   ::.:
Worm   861 EEAQKQADRLLNS-------MLPKSIAEDLKIGKPVLPQLY----SCATVLFSDIRGFTRISSTS 914

  Fly   868 AGLRI---LHEIICCFDDLLVDYQTRYKIEKIKVMGWTYMVACGLETDHYTDFSIDIPVKQPEAD 929
            ..|::   |:::...||.::..:.. ||:|.|   |..||:..|:.|::
Worm   915 TPLQVVTFLNDMFSGFDAIIAKHDA-YKVETI---GDAYMIVSGVPTEN---------------- 959

  Fly   930 SEIRRGSSVLTVHFGSTEDDEMSGDNVSQPYAQ-VQDVAVLVMTEFALDLLRIMHDIRYNYVFSE 993
                 |:|                      :|| :.||| |.|..|..           |:..:.
Worm   960 -----GNS----------------------HAQNIADVA-LKMRAFIC-----------NFKLAH 985

  Fly   994 YDTFLTGSLKIGISHGSVMAGVVGLSKPHYDIWGHTVNMASRMSSTGLLDNIQVTRHTAKVLRQF 1058
            ....|. .::||...|.|.||||||:.|.|.::|.|||.||||.|||:.:.||::.....:|..|
Worm   986 RPEELM-MVRIGFHSGPVAAGVVGLAAPRYCLFGDTVNTASRMESTGVANKIQISEGAYNLLHCF 1049

  Fly  1059 --NIRCNYRGHTEVKGVGKVPTY 1079
              ..:...||..||||.|:..||
Worm  1050 FPQFQMVERGKIEVKGKGECLTY 1072

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32305	NP_728725.2	CYCc	251..449	CDD:214485
		Nucleotidyl_cyc_III	292..445	CDD:299850
		CYCc	814..1056	CDD:214485	66/249 (27%)
		Nucleotidyl_cyc_III	845..1081	CDD:299850	68/244 (28%)
gcy-9	NP_509897.3	Periplasmic_Binding_Protein_Type_1	66..416	CDD:299141
		ANF_receptor	69..404	CDD:279440
		PKc_like	550..820	CDD:304357
		HNOBA	<837..883	CDD:285003	10/28 (36%)
		CYCc	862..1054	CDD:214485	71/262 (27%)
		Guanylate_cyc	889..1076	CDD:278633	69/248 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810