Protein Alignment CG32305 and acy-4

DIOPT Version :9

• Sequence 1: NP_728725.2
• Gene: CG32305 / 317967
• FlyBaseID: FBgn0052305
• Length: 1164
• Species: Drosophila melanogaster
• Sequence 2: NP_504486.4
• Gene: acy-4 / 178949
• WormBaseID: WBGene00000071
• Length: 1013
• Species: Caenorhabditis elegans
• Alignment Length: 1084
• Identity: 266/1084 - (24%)
• Similarity: 459/1084 - (42%)
• Gaps: 260/1084 - (23%)

  Fly    96 FIMLLSMQNNVGMITNTLISWLMALFLTSMDLVSDLLGTIYS-----------------GAAYPT 143
            |::|||:..:....:.....||.:|.|..:.||..:|...::                 .|....
 Worm    98 FVILLSICISEAAFSAFGAEWLKSLILCILTLVISILSFFHAKRTELVCIASIISCVIISACTSM 162

  Fly   144 VPCYDHVVLVSVYMTLPIAF-YQGSSVYVLGMVVSIIYIGYAFYMQYLNDQVSFYLLASYAIYLF 207
            .....::::.|.|..||::| ....|.:.|..:|:.|.:    .|.|   .|.|.::.:..:.:.
 Worm   163 RTSVTYLLIFSTYSLLPMSFMLMIFSTFALTFLVAFIGV----LMDY---NVGFDIILTRVMMVI 220

  Fly   208 TLNLIFSFFTIIRDYGLRRAILSRYQLVYQNIVYQLVMKKENGLLESILPRKMIRTLQEEICSRI 272
            .:|::.|......::..|:......:.|...::....|.::..:|.::||:.:...::
 Worm   221 LVNVVGSLVYYPTEFVQRKTFHETRKCVQSRMLLDKEMHRQEKILLAVLPKNIAFEVK------- 278

  Fly   273 EDQDKNFTPSKAGLRKLFLEPYPNVSILVADMVNYTHLTTTLEAPQLVEILHDLFVNFDLAANRN 337
              :|...|..:....|:::..|.::|||.||:..:|:|.:......||.:|::||..||..|:.:
 Worm   279 --KDMQETHEERMFHKIYIRKYEDISILFADICGFTNLASEYNPKDLVLMLNELFARFDKVASIH 341

  Fly   338 RAMRIKFLGDSYNCVAGIPNYFPAHASCCVDQALEMIHITQGVSSRRELDINLRIGVHSGEVFAG 402
            :.||||.|||.|.||.|:|.|...||...|:...:||...:.|.....:::|:|:|:|:|:...|
 Worm   342 QCMRIKILGDCYYCVCGVPEYQKNHAINTVEMGRDMIEAIRLVREMTLVNVNMRVGIHTGKAHCG 406

  Fly   403 IIGHTKWQFDIWSKDVDITNRLESSGLPGLVHVSQRTLSMLDEHYIFREGTEAAKNDPILQQAGI 467
            ::|..|||||:||.||.:.|::||.||.|.||::..|.|.|...||..||...::: ..|::..|
 Worm   407 VLGLKKWQFDVWSNDVTLANQMESGGLAGRVHITDATRSYLKGAYILEEGNGGSRS-KFLEKEKI 470

  Fly   468 RTFLVSNRLPDAVEPGELDDELSSASINSCRLSYGGYYEEIQIKAQREIMKEVDQMAVGH-CFIE 531
            :|:||.:|.||                          |:.|            .|.|..| ..:.
 Worm   471 KTWLVVDRSPD--------------------------YDNI------------CQEATNHPVMVP 497

  Fly   532 WRRSSSMKKQD------------------FNEEYLFSN-QIHLVLGV----FRSWK----REW-- 567
            |:.:..:.||:                  ..||.|..| ..||..|:    ..:||    :.|
 Worm   498 WKSTRGISKQERLTGMSTRTRGASTRNGLSEEEVLVENVDSHLRQGIQAIHQENWKTMHCKNWSL 562

  Fly   568 --------------EFHNLPDLMIKYTMLLVLCAGLAIMSINLIEEATYPDILVLLGILLILLIL 618
                          ::.::|..:..|..::.:|.|:....:||:..:..|.:.::|..::|.:
 Worm   563 KYKQVRVENKFVRLKYKDIPFQVTLYVAIVAICIGIKFGLMNLVSFSFVPQMFIVLTSVMIFI-- 625

  Fly   619 CILAGYKKLRLQWKKLTPMSQPSCFLSRWLL---RISERIEDSLFVRIPLTMVVLLLLYVMSSQA 680
                                     |:|.|:   |:...:...||:.:.:.:|:|:.:|    ::
 Worm   626 -------------------------LTRALIKHARLVSLVIGVLFILLSIQIVILMGMY----ES 661

  Fly   681 VFSCDVAKLELSIIEAHLYNEKSYAECFGPWTVTYCVVIVISLLFVVPGCPLVIKILAGLLILGL 745
            .|:|||.|       ....|...:.|.|...|:..||::.:..:         .|:|..::
 Worm   662 KFTCDVEK-------CFKNNYTDFFEIFEICTLATCVILSVDFM---------TKLLMSMI---- 706

  Fly   746 HLGTVHLYYGFAFERSETTDL-------GLKSDYAHTWYLVALFIVLVL-RERHVNYLRKFNYFM 802
                    |..:|....|..|       .|.|.||:...|..|.::||: ..|....:.::::..
 Worm   707 --------YFSSFTVLITAKLIRINQYEALLSTYANFCVLSCLTLLLVVFSTRRSELISRYDFIW 763

  Fly   803 RVCYEEAHQQTDEKLRSIKIIMANILPTHVAQVY-KVRRPHDQLYYENFSKVAVMFASIENF--- 863
            ::...:...|...|....:.::.||||:|||:.: :......:||:|:.....:|||::..|
 Worm   764 KLQALDEQLQMKRKHEQNRSVLENILPSHVAKHFVEDATSVSKLYHESRDNACIMFATLTEFDKF 828

  Fly   864 -------NADTAGLRILHEIICCFD---DLLVDYQTRYKIEKIKVMGWTYMVACGLETDHYTDFS 918
                   |.....||:|:|||..||   |.::|.:...||||||.:..|||||.||
 Worm   829 YIECDGNNEGVECLRLLNEIISDFDQILDQILDREEFKKIEKIKTISTTYMVASGL--------- 884

  Fly   919 IDIPVKQPEADSEIRRGSSVLTVHFGSTEDDEMSGDNVSQPYAQVQDVAVLVMTEFALDLLRIMH 983
                     |..|                    .|||     :.|:.:|:     ||.:||..:.
 Worm   885 ---------AGRE--------------------CGDN-----SHVEAIAL-----FARELLVKLE 910

  Fly   984 DIRYNYVFSEYDTFLTGSLKIGISHGSVMAGVVGLSKPHYDIWGHTVNMASRMSSTGLLDNIQVT 1048
            .       :...:|...:|:|||:.|.|:|||:|..||||||||::||:||||.|.|:...||||
 Worm   911 S-------TNIHSFNNFNLRIGINVGPVVAGVIGSDKPHYDIWGNSVNVASRMDSGGVAGRIQVT 968

  Fly  1049 RHTAKVLRQ--FNIRCNYRGHTEVKGVGKVPTYLVVVDPDLTFQ 1090
            .....:|..  :|..|  ||...|||.|.:.|:.::...|...|
 Worm   969 EEVKSILEPLGYNFEC--RGQINVKGKGMMETFFLLPPEDFDCQ 1010

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32305	NP_728725.2	CYCc	251..449	CDD:214485	69/197 (35%)
		Nucleotidyl_cyc_III	292..445	CDD:299850	62/152 (41%)
		CYCc	814..1056	CDD:214485	81/255 (32%)
		Nucleotidyl_cyc_III	845..1081	CDD:299850	83/250 (33%)
acy-4	NP_504486.4	AC_N	<50..291	CDD:292831	35/208 (17%)
		CYCc	260..451	CDD:214485	68/199 (34%)
		Guanylate_cyc	293..448	CDD:278633	61/154 (40%)
		CYCc	778..984	CDD:214485	82/260 (32%)
		Guanylate_cyc	807..1003	CDD:278633	83/252 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45627
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910