Protein Alignment CG32305 and acy-3

DIOPT Version :10

• Sequence 1: NP_728725.2
• Gene: CG32305 / 317967
• FlyBaseID: FBgn0052305
• Length: 1164
• Species: Drosophila melanogaster
• Sequence 2: NP_497765.4
• Gene: acy-3 / 175489
• WormBaseID: WBGene00000070
• Length: 1243
• Species: Caenorhabditis elegans
• Alignment Length: 1183
• Identity: 237/1183 - (20%)
• Similarity: 429/1183 - (36%)
• Gaps: 305/1183 - (25%)

  Fly    24 LEWRHLKNKCQNLRLELACSRLRELALM----SNVVQIIWHVE---LLMVAHVILLLALVKDIIL 81
            |:|||           .|.:||..:.|.    |..::.:.|:.   .|..| |||||:.|..|..
 Worm    13 LDWRH-----------AASARLIRIVLFITSGSAFLRTLGHIPGFYALWTA-VILLLSTVTIIFH 65

  Fly    82 VTMVPYFAVMLFSPFIMLLSMQNNVGMITNTLISWLMALFLTSMDLVSDLLGTIYSGAAYPTVPC 146
            :......|.......|:||                        :|:...|.|  |. :.:|.:
 Worm    66 ILRPARIAAFQILAGIVLL------------------------LDVAFALPG--YE-SLFPAL-- 101

  Fly   147 YDHVVLVSVYMTLPIAFYQGSSVYVLGMVVSIIY-IGYAFYMQYLNDQVSFYLLASYAIYLFTLN 210
               :.:.|:|....:.||   ::.....::||:. ..:..:::.|:..   .|||...::::| |
 Worm   102 ---LAVFSLYTFFSLPFY---AILATSTLISIVQTCSFLLFVEPLHTN---ELLAIIVVHIWT-N 156

  Fly   211 LIFSFFTIIRDYGLRRAILSRYQLVYQNIVYQLVMKKENGLLESILPRKMIRTLQEEICSRIEDQ 275
            ....:.....|...|.|.||...........:....:.|.||.|.||..:|...:.:|..
 Worm   157 FTGIYLCSTADRLARNAFLSARNSSEAESTAEFQSNRLNKLLSSFLPYHLINQARHQITL----- 216

  Fly   276 DKNFTPSKAGLRKLFLEPYPNVSILVADMVNYTHLTTTLEAPQLVEILHDLFVNFDLAANRNRAM 340
               :.|      .|:.|.|..||:....:|.:..:.....:.....:|.:|....:..|..|...
 Worm   217 ---YKP------HLYNETYSQVSVAYGRLVGFESVLAQCSSIDAARVLKELDSRIERLAASNGCT 272

  Fly   341 RIKFLGDSYNCVAGIPNYFPAHAS--CCVDQALEMIHITQGVSSRRE---LDINLRIGVHSGEVF 400
            |:  ..:....|..||.....||:  |.....||.:     ::|.|:   .|:::.||:.||.|.
 Worm   273 RV--ASEGITAVCSIPGIDSQHATKLCRFSMELETL-----INSFRDATGADVSVCIGIDSGPVT 330

  Fly   401 AGIIGHTKWQFDIWSKDVDITNRLESSGLPGLVHVSQRTLSMLDEHYIFREGTEAAKNDPILQQA 465
            ||::|.:||.:|:.....|....::|:.....|:||..|...|.....|.           |::.
 Worm   331 AGVVGVSKWHYDVIGSVFDNALLMQSNATEPGVYVSNETRRFLGSTGEFE-----------LEKC 384

  Fly   466 GI-----------RTFLVSNRLPDAVEPGELDDELSS-ASINSCRLSYGGYYEEIQIKAQREIMK 518
            .|           ..|.|:.|......|..::..|.| .::|....:.|...:....|:|.:.
 Worm   385 PIGWKLYGHLPSPELFPVNKRFSLVTVPQAVNRVLQSIVAMNPTLKTMGTNKKRKGEKSQEKF-- 447

  Fly   519 EVDQMAVGHCFIEWRRSSSMKKQDFNEEYLFSNQIHLVLGVFRSWKREWEFHNLPDLMIKYTMLL 583
            ::.:..|.|..|....|...:......||                .:|.:...:|.|.|....|:
 Worm   448 DMQKKKVEHSTIISTLSQRFRNPGLEAEY----------------HKETDHWFIPSLAISIFFLV 496

  Fly   584 V------LCAGLAIMSINLIEEATYPDILVLLGILLILLILCILAGYKKLRLQWKKLTPMSQPSC 642
            |      |.....|.|:.||..|    :.|:..|||:|.|                       ..
 Worm   497 VYGIYHMLVMPRLITSLALIVGA----LTVMFFILLMLYI-----------------------DY 534

  Fly   643 F--LSRWLLRISERIEDSLFVRIPLTMVVLLLLYVMSSQAVFSC------DVAKLELSIIEAHLY 699
            |  .|:::.|.|.....|:       ::::::|:|......|||      ||.:      :||.
 Worm   535 FHTFSQFITRTSAGHAVSI-------ILIIVILFVCGIVNTFSCPQPNAPDVCQ------KAHF- 585

  Fly   700 NEKSYAECFGPWTVTYCVVIVISLLFVVPGCPLVIKILAGLLILGLHLGTVHLY------YGFAF 758
              .:|:  |..||:|..|.:..      |...|.|.::..||..||     .:|      :|
 Worm   586 --STYS--FAMWTITTAVFVRF------PSVYLAILLIISLLTYGL-----QIYVTRPDEFG--- 632

  Fly   759 ERSETTDLGLKSDYAHTWYLVALFIVLVLRERHVNYLRKFNYFMRVCYEEAHQQTDEKLRSIKII 823
            .|...|:|.|      :.:|::|..::.|..|....|.:.::...|...|.....|:.:.....:
 Worm   633 PREFMTELDL------SCFLISLVSMVFLHSRRCERLLRLDFLAVVKGIEETSMKDKLINLNNQM 691

  Fly   824 MANILPTHVAQVYKVRRPHDQLYYENFSKVAVMFASIENFNAD-TAGLRILHEIICCFDDLLVDY 887
            :.|::|.|||.  .|.:....:::.:...|.:.:.::..|:.: .||:..|:.:...||..:.:|
 Worm   692 LLNLVPAHVAP--GVIQKAGDVWHHSHQSVGIAYIAVSGFDLEGEAGINGLNYVFSHFDQAIANY 754

  Fly   888 QTRYKIEKIKVMGWTYMVACGLETDHYTDFSIDIPVKQPEADSEIRR-----GSSVLTV-HFGST 946
            :   .:||:|.....|:||.||               .|:|...:..     |..:.|: ||
 Worm   755 K---GVEKVKSANRFYIVAVGL---------------LPDAAQNVNETPWTIGELMSTLAHF--- 798

  Fly   947 EDDEMSGDNVSQPYAQVQDVAVLVMTEFALDLLRIMHDIRYNYVFSEYDTFLTGSLKIGISHGSV 1011
                                 ::.:::||::              :|:      .::||:..||.
 Worm   799 ---------------------IISISQFAME--------------NEF------HVQIGVDCGST 822

  Fly  1012 MAGVVGLSKPHYDIWGHTVNMASRMSSTGLLDNIQVTRHTAKVLRQFNIR---------CNYRGH 1067
            :|.|....:|.|:|:|.|::.:..:......|...|:......||...:|         .|...:
 Worm   823 LAFVANTDQPRYEIFGETLDRSRTLMQAAGHDTTLVSEEVFLALRPRPLRFSSQPVKVAMNLNAY 887

  Fly  1068 TEVKGVGKVPTYLVVVD-PDLTFQDHDQVSMSMKD----SKSWVIDT----LSLSFTPSFVPPKS 1123
            ..|.|:..|.     || |.:..::.::.:..|.:    ::|.:.||    ::.|...||.....
 Worm   888 ELVTGLRDVS-----VDIPTMPREEQERHTQGMVEAQFANQSRMYDTQTSEMASSMASSFSSELR 947

  Fly  1124 STSDEEEAEGELE 1136
            |...:.|.:.:||
 Worm   948 SIDGDAETDSDLE 960

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32305	NP_728725.2	AcyC	62..451	CDD:441717	85/397 (21%)
		Nucleotidyl_cyc_III	292..445	CDD:448371	39/157 (25%)
		Nucleotidyl_cyc_III	845..1081	CDD:448371	45/251 (18%)
acy-3	NP_497765.4	AcyC	6..380	CDD:441717	94/438 (21%)
		Nucleotidyl_cyc_III	221..382	CDD:448371	41/178 (23%)
		CYCc	696..873	CDD:214485	45/240 (19%)