Protein Alignment CG32305 and adcy1

DIOPT Version :9

• Sequence 1: NP_728725.2
• Gene: CG32305 / 317967
• FlyBaseID: FBgn0052305
• Length: 1164
• Species: Drosophila melanogaster
• Sequence 2: XP_002933461.1
• Gene: adcy1 / 100492373
• XenbaseID: XB-GENE-950909
• Length: 1122
• Species: Xenopus tropicalis
• Alignment Length: 1150
• Identity: 308/1150 - (26%)
• Similarity: 507/1150 - (44%)
• Gaps: 232/1150 - (20%)

  Fly    23 DLEWRHLKNKCQNLRLEL-ACSRLRELALMSNVVQIIWHVELLM-----------VAHVILLLAL 75
            :.:.:.|::..||..|:| ..|.|:.||::..:...:..:||:.           ..|.|:.|:|
 Frog    37 EFDCKELESLFQNYNLKLEQTSTLKALAVLIIMTGTLALLELMSGPSLTISKGSHPVHCIIFLSL 101

  Fly    76 VKDIILVTMVPYFAVMLFSPFIMLLSMQNNVGMITNTLISWLMALFLTSMDLVSDLLGTIYSGAA 140
                .:||.|.|..|......:.|            ||:......||...          :|..|
 Frog   102 ----FIVTNVKYLQVTQLQQIVKL------------TLLFGFTFSFLCCP----------FSLGA 140

  Fly   141 YPTVPCYD------HVVLVS--VYMTLPIAFYQGSSVYVLGMVVSIIYIGYAFYMQYLNDQVSFY 197
            |...|...      .::||:  .|..||:   :.....|.|.:||:.:|...........:..:.
 Frog   141 YGLEPPVSSEQGLWQLMLVTFVAYALLPV---RTLLAIVFGFMVSVSHIIVTATSISPKKKRLWR 202

  Fly   198 LLASYAIYLFTLNLIFSFFTIIRDYGLRRAILSRYQLVYQNIVYQLVMKKENGLLESILPRKMIR 262
            .|...||...::||...|..|:.:...|:|.|.....:...:..:...:|:..||.|:|||.:..
 Frog   203 TLVVNAILFVSVNLSGVFVRILTERAQRKAFLQARNCIEDRLRLEDENEKQERLLMSLLPRNVAM 267

  Fly   263 TLQEEICSRIEDQDKNFTPSKAGLRKLFLEPYPNVSILVADMVNYTHLTTTLEAPQLVEILHDLF 327
            .::|:.          ..|.:....|::::.:.|||||.||:|.:|.|.:...|.:||::|::||
 Frog   268 EMKEDF----------LKPPERIFHKIYIQRHDNVSILFADIVGFTSLASQCTAQELVKLLNELF 322

  Fly   328 VNFDLAANRNRAMRIKFLGDSYNCVAGIPNYFPAHASCCVDQALEMIHITQGVSSRRELDINLRI 392
            ..||..|..|...|||.|||.|.||:|:......||.|||:..|:||.....|:...|:|:|:|:
 Frog   323 GKFDELATENHCRRIKILGDCYYCVSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRV 387

  Fly   393 GVHSGEVFAGIIGHTKWQFDIWSKDVDITNRLESSGLPGLVHVSQRTLSMLDEHYIFREGTEAAK 457
            |:|:|.|..|::|..|||:|:||.||.:.|.:|:.||||.||:::.||..|:..|....|....:
 Frog   388 GLHTGRVLCGVLGLRKWQYDVWSNDVTLANVMEAGGLPGKVHITKNTLECLNGDYEVEPGYGHER 452

  Fly   458 NDPILQQAGIRTFLVSNRLPDAVEPGELDDELSSASINSCRLSYGGY-YEEIQIKAQREIMK-EV 520
            |. .|::..|.||.:.......:.||.:..::..|.    |:.:... |..:|:...|::.| |:
 Frog   453 NS-FLKKHNIETFFIVPSHRRKIFPGLILSDIKPAK----RMKFKTVCYLLVQLMHCRKMFKAEI 512

  Fly   521 DQMAVGHCFIEWR----RSSSMKKQDFNEEYLFSNQIHLVLGV---------------------- 559
            ....|..|..:.:    |::|.|.:  |.....:|.||...|.
 Frog   513 PFSNVMTCEDDDKRRALRTASEKLR--NRSSFSTNVIHNTPGTRVNRYIGRLIEARQTDSEMSDL 575

  Fly   560 ------FRSWKREWEFHNLPDLMIKY-----TMLLVLCAGLAIMSINLIEEATYPDILVLLGILL 613
                  ::..:||.::|.|.|   :|     .:.|:|.|...::.:.:..::|.  :|:||...|
 Frog   576 NFITLKYKHIEREQKYHQLHD---EYFTSAVVLSLILAALFGLVYLLIFPQSTI--VLILLVFCL 635

  Fly   614 ILLILCILAGYKKL-RLQWKKLTPMSQPSCFLSRWLLRISERIEDSLFVRIPLTMVVLLLLYVMS 677
            ..|:.||:  |..: |:|       ..|.|.              ::.:|..|.:.:::|:|.::
 Frog   636 CFLVACIM--YLHVTRVQ-------CFPGCL--------------TIQIRTILCIFIVILIYSVA 677

  Fly   678 SQAVFSCDV----AKLELSII------EAHLYNEKSYAEC-FGPWTVTYCVVIVISL-LFV-VPG 729
            ...|..|..    :....||:      |....||:   .| ...:|...|||..:|| :|: :..
 Frog   678 QGCVVGCMPWIWRSNNSSSIVIITPKGENKTMNER---PCDTAHYTFLSCVVGTLSLAIFLRISS 739

  Fly   730 CPLVIKIL--AGLLILGLHLGTVHLYYGFAFERSETTDLGLKSDYAHTWYLVALFIVLVLRERHV 792
            .|.::.:|  ..|.|:.|.:.        .:.::...|......|.....::.....|.|..|.|
 Frog   740 FPKMVLLLFVTILYIVILEIS--------GYRKTLGGDTSYMRGYEPILAILLFSCSLALHSRQV 796

  Fly   793 NYLRKFNYFMRVCYEEAHQQTDEKLRSIKIIMANILPTHVAQVYKVRRPHD-QLYYENFSKVAVM 856
            :...:.:|...|..||.....:......|.|:.|:||.||||.:.:..|.: .|||:::|:|.||
 Frog   797 DLKLRLDYLWAVQAEEERDDMERVKLDNKRILFNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVM 861

  Fly   857 FASIENFN-------ADTAG---LRILHEIICCFDDLLVDYQTRYK-IEKIKVMGWTYMVACGLE 910
            ||||.|||       .:..|   ||:|:|||..||:|:  .:..|| |||||.:|.|||.|.||
 Frog   862 FASIPNFNDFYIELDGNNMGVECLRLLNEIIADFDELM--EKECYKDIEKIKTIGSTYMGAVGL- 923

  Fly   911 TDHYTDFSIDIPVKQPEADSEIRRGSSVLTVHFGSTEDDEMSGDNVSQPYAQVQDVAVLVMTEFA 975
                      :|....:|...|                           |:.:..:|     :|:
 Frog   924 ----------VPTTGTKAKKSI---------------------------YSHLSTLA-----DFS 946

  Fly   976 LDLLRIMHDIRYNYVFSEYDTFLTGSLKIGISHGSVMAGVVGLSKPHYDIWGHTVNMASRMSSTG 1040
            :::..::.:|.|    ..|:.|:   |::||:.|.|:|||:|..:|.|||||:|||:||||.|||
 Frog   947 IEMFDVLDEINY----QSYNEFV---LRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTG 1004

  Fly  1041 LLDNIQVTRHTAKVLRQFNIRCNY----RGHTEVKGVGKVPTYLV 1081
            :...||||....::|:.    |||    ||...|||.|::.||.:
 Frog  1005 VQGKIQVTEDVHRILKS----CNYEFVCRGKVSVKGKGEMLTYFL 1045

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32305	NP_728725.2	CYCc	251..449	CDD:214485	78/197 (40%)
		Nucleotidyl_cyc_III	292..445	CDD:299850	68/152 (45%)
		CYCc	814..1056	CDD:214485	87/253 (34%)
		Nucleotidyl_cyc_III	845..1081	CDD:299850	89/250 (36%)
adcy1	XP_002933461.1	AC_N	<37..282	CDD:292831	58/283 (20%)
		CYCc	248..443	CDD:214485	78/204 (38%)
		Guanylate_cyc	284..466	CDD:278633	75/182 (41%)
		CYCc	817..1028	CDD:214485	91/266 (34%)
		Guanylate_cyc	850..1047	CDD:278633	89/251 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910