Protein Alignment CG32305 and adcy7

DIOPT Version :9

• Sequence 1: NP_728725.2
• Gene: CG32305 / 317967
• FlyBaseID: FBgn0052305
• Length: 1164
• Species: Drosophila melanogaster
• Sequence 2: NP_001106549.1
• Gene: adcy7 / 100127741
• XenbaseID: XB-GENE-1005225
• Length: 1061
• Species: Xenopus tropicalis
• Alignment Length: 1114
• Identity: 298/1114 - (26%)
• Similarity: 504/1114 - (45%)
• Gaps: 241/1114 - (21%)

  Fly    54 VVQIIWHVELLMVAHVILLLALVKDIILV---TMVPYFAVMLFSPFIML-LSMQNNVGMITNTLI 114
            |..::.::.||.:.:|     |..|..:|   ..||:|..:.||.:.|| |.||
 Frog    96 VFSLVIYICLLTIGYV-----LTYDSSVVHAWDQVPFFLFITFSVYTMLPLGMQ----------- 144

  Fly   115 SWLMALFLTSMDLVSDLLGTIYSGAAYPTVPCYDHVVLVSVYMTLPIAFYQGSSVYVLGMVVSII 179
                          :.|:.:|.||.:        |::::|:.:.|.    .||
 Frog   145 --------------ACLIVSIISGIS--------HIIVISITVVLS----SGS------------ 171

  Fly   180 YIGYAFYMQYLNDQVSFYLLASYAIYLFTLNLIFSFFTIIRDYGLRRAILSRYQLVYQ--NIVYQ 242
                       ||.::|.|:|:..|:|.. ||:.::    ..|.::.|....|....:  .|..:
 Frog   172 -----------NDAIAFQLMANAVIFLCG-NLMGAY----HKYHMQDASRDLYSYTVKCIRIKMK 220

  Fly   243 LVMKK--ENGLLESILPRKMIRTLQEEICSRIEDQDKNFTPSKAGLRKLFLEPYPNVSILVADMV 305
            |.:||  :..||.|:||..:...::..|..|:.:.:.|..|.. ....|:::.:.|||||.||:|
 Frog   221 LELKKRQQESLLLSVLPVYISMEMKLAIQDRLTETNDNRQPDN-NFHSLYVKRHQNVSILYADIV 284

  Fly   306 NYTHLTTTLEAPQLVEILHDLFVNFDLAANRNRAMRIKFLGDSYNCVAGIPNYFPAHASCCVDQA 370
            .:|.|.:.....:||.:|::||..||..|..|..||||.|||.|.||:|:|...|.:|..||...
 Frog   285 GFTRLASDCSPKELVVMLNELFGKFDQIAKENECMRIKILGDCYYCVSGLPVSLPNNAKNCVKMG 349

  Fly   371 LEMIHITQGVSSRRELDINLRIGVHSGEVFAGIIGHTKWQFDIWSKDVDITNRLESSGLPGLVHV 435
            |::....:.|......|||:|:|||||.|..|:||..|||||:||.||.:.||:||:||||.||:
 Frog   350 LDICEAIKQVREATGADINMRVGVHSGNVLCGVIGLRKWQFDVWSHDVSLANRMESAGLPGRVHI 414

  Fly   436 SQRTLSMLDEHYIFREGTEAAKNDPILQQAGIRTFLVSNRLPDAVEPGELDDELSSASIN----- 495
            ::.||..::..|...|| .....||.|::..|:||||.:  |.|......::.|:...:|
 Frog   415 TEATLKHMNGAYDVEEG-HGELRDPYLKEMNIKTFLVID--PRAKNSRVKNNHLTRHRVNDGIKV 476

  Fly   496 --SCRL-----SYG-----GYYEEIQIKAQR------EIMKEVDQMAVGHCFIEWRRSSSMKKQD 542
              |.|:     |:|     .::::....:..      :...|:....:|.. ::..|:.|.|:.
 Frog   477 RPSVRMTRYLESWGAARPFSHFDQTDASSTEVPTVNGKPKPEIPLKGMGRT-VKTERNVSQKRN- 539

  Fly   543 FNEEYLFSNQIHLVLGV--FRSW-------------------KREWEFHNLPDLMIKYTMLLVLC 586
             .||.|....::.:.|:  .:.|                   ::|:....:|.:...:     ||
 Frog   540 -QEEELHDRMMNTIDGLSSAKPWFGKTDDFYGFLLFFTADGLEKEYRTFRIPCIQSYF-----LC 598

  Fly   587 AGLAIMSINLIEEATYP---DILVLLGILLILLILCILAGYKKLRLQWKKLTPMSQPSCFLSRWL 648
            |.|..:.|.||:....|   ::.:..|::.:|::..:|..|.      .|.......:...||:|
 Frog   599 ASLIFLCIFLIQILVMPRSANLGISFGVVSVLILWVLLICYV------DKCARFCNENAPFSRFL 657

  Fly   649 LRISERIEDSLFVRIPLTMVVLLLLYVMS------SQAVFSCDVAKLELSIIEAHLYNEKSYAEC 707
            ..:.|.||....:|:||..:.|..|.::|      .|.:.:|:.:.:            .:.::|
 Frog   658 CSLVEMIETRPSLRVPLVALTLGSLLIISIVNLPLDQTLQTCNTSSI------------ATESQC 710

  Fly   708 FG-PWTVTYCVVIVISLLFVVPGCPLVIKILAGLLILGLHLGTVHLYYGFA--FERSETTDLGLK 769
            .. |:.|..|::.:::....:..| ..:|||  ||........|.:::..:  |..:..:.:|:.
 Frog   711 QSIPYYVYCCILGLVACSMFLRMC-FELKIL--LLTAAFTAYNVIIFHTHSSIFRSNLNSSIGVL 772

  Fly   770 SDY--AHTWYLVALFIVLVLRERHVNYLRKFNYFMRVC-YEEAHQQTDEKLRSI----KIIMANI 827
            .|:  ...:||...::.|||..|.|.|..:.:     | ::...::.||::.::    ::::.|:
 Frog   773 EDFQKMSCFYLSLYYLTLVLLARQVEYYSRLD-----CLWKRKFRKEDEEIETMENLNQLLLENV 832

  Fly   828 LPTHVAQVY-KVRRPHDQLYYENFSKVAVMFASIENF-------NADTAG---LRILHEIICCFD 881
            ||.|||..: ...|.::.||::::..|.|||||:..|       :.:..|   ||:|:|||..||
 Frog   833 LPAHVAAYFIDDNRSNEDLYHQSYDCVCVMFASVPEFKVFYTECDVNKEGLECLRLLNEIIADFD 897

  Fly   882 DLLVDYQTRYK-IEKIKVMGWTYMVACGLETDHYTDFSIDIPVKQPEADSEIRRGSSVLTVHFGS 945
            :||:  :.::. :||||.:|.|||.|.|                              ||...|.
 Frog   898 ELLM--KPKFSGVEKIKTIGSTYMAATG------------------------------LTATPGQ 930

  Fly   946 TEDDEMSGDNVSQPYAQVQDVAVLVMTEFALDLLRIMHDIRYNYVFSEYDTFLTGSLKIGISHGS 1010
            ...|:           :.|...:.:..|:|:.|:..:..|. .:.|:.:      .|::||:||.
 Frog   931 ENQDQ-----------EKQHALIGITVEYAMALMSKLDGIN-RHSFNNF------RLRVGINHGP 977

  Fly  1011 VMAGVVGLSKPHYDIWGHTVNMASRMSSTGLLDNIQVTRHTAKVLRQFNIRCNYRGHTEVKGVGK 1075
            |:|||:|..||.|||||:|||:||||.|||.|..||||..|.::|......|..||...|||.|:
 Frog   978 VIAGVIGAKKPQYDIWGNTVNVASRMESTGELGKIQVTEETCQILEGLGYSCECRGFINVKGKGE 1042

  Fly  1076 VPTYLVVVD 1084
            :.||.|..|
 Frog  1043 LRTYFVCTD 1051

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32305	NP_728725.2	CYCc	251..449	CDD:214485	82/197 (42%)
		Nucleotidyl_cyc_III	292..445	CDD:299850	71/152 (47%)
		CYCc	814..1056	CDD:214485	82/257 (32%)
		Nucleotidyl_cyc_III	845..1081	CDD:299850	83/246 (34%)
adcy7	NP_001106549.1	AC_N	<21..266	CDD:318454	51/240 (21%)
		Guanylate_cyc	268..418	CDD:306677	70/149 (47%)
		DUF1053	483..591	CDD:399378	13/110 (12%)
		Guanylate_cyc	851..1048	CDD:306677	83/246 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D181177at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45627
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020