DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12111 and SFTPD

DIOPT Version :9

Sequence 1:	NP_001259341.1	Gene:	CG12111 / 31796	FlyBaseID:	FBgn0030050	Length:	188	Species:	Drosophila melanogaster
Sequence 2:	NP_003010.4	Gene:	SFTPD / 6441	HGNCID:	10803	Length:	375	Species:	Homo sapiens

Alignment Length:	128	Identity:	38/128 - (29%)
Similarity:	60/128 - (46%)	Gaps:	17/128 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 IGDNYY----YIEPMNKVNWFQAAGACRMMNAHLASIEDKPEMEALIKYMKAKGFKNNDYFWISG 111
            :|:..:    :::|..     :|...|......|||.....|..||.:.:.||    |:..::|.
Human   260 VGEKIFKTAGFVKPFT-----EAQLLCTQAGGQLASPRSAAENAALQQLVVAK----NEAAFLSM 315

  Fly   112 NDLGTEGAFYWMSNGRPMTYAPWNGPKQMPDNYGGNENCVHMFATREMINDANCKIQMLYVCE 174
            .|..|||.|.: ..|..:.|:.| .|.: |::.||:|:||.:| |....||..|..:.|.|||
Human   316 TDSKTEGKFTY-PTGESLVYSNW-APGE-PNDDGGSEDCVEIF-TNGKWNDRACGEKRLVVCE 374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12111	NP_001259341.1	CLECT	55..174	CDD:153057	35/122 (29%)
SFTPD	NP_003010.4	Collagen	46..98	CDD:189968
		Collagen	130..201	CDD:189968
		Surfac_D-trimer	224..269	CDD:286141	1/8 (13%)
		CLECT_collectin_like	262..375	CDD:153061	37/126 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910