DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12111 and FCER2

DIOPT Version :9

Sequence 1:	NP_001259341.1	Gene:	CG12111 / 31796	FlyBaseID:	FBgn0030050	Length:	188	Species:	Drosophila melanogaster
Sequence 2:	NP_001207429.1	Gene:	FCER2 / 2208	HGNCID:	3612	Length:	321	Species:	Homo sapiens

Alignment Length:	149	Identity:	41/149 - (27%)
Similarity:	61/149 - (40%)	Gaps:	14/149 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 TNYRTEVYNGIPSEIDTTP--FVRIGDNYYYIEPMNKVNWFQAAGACRMMNAHLASIEDKPEMEA 91
            |..|.|:........:|.|  ::......||.....| .|..|..||..|...|.||....|.:.
Human   146 TKLRMELQVSSGFVCNTCPEKWINFQRKCYYFGKGTK-QWVHARYACDDMEGQLVSIHSPEEQDF 209

  Fly    92 LIKYMKAKGFKNNDYFWISGNDLGTEGAFYWMSNGRPMTYAPWNGPKQMPDNYGGNENCVHMFAT 156
            |.|:....|      .||...:|..:|.|.|: :|..:.|:.| .|.: |.:....|:||.|..:
Human   210 LTKHASHTG------SWIGLRNLDLKGEFIWV-DGSHVDYSNW-APGE-PTSRSQGEDCVMMRGS 265

  Fly   157 REMINDANCKIQM-LYVCE 174
            ... |||.|..:: .:||:
Human   266 GRW-NDAFCDRKLGAWVCD 283

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12111	NP_001259341.1	CLECT	55..174	CDD:153057	35/119 (29%)
FCER2	NP_001207429.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	66..85
		Repetitive region	69..89
		RILP-like	<77..153	CDD:304877	3/6 (50%)
		Repetitive region	90..110
		Repetitive region	111..131
		CLECT	163..282	CDD:214480	35/129 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	290..321
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X73
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.910