DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Trf4-1 and mtpap

DIOPT Version :9

Sequence 1:	NP_001259340.1	Gene:	Trf4-1 / 31795	FlyBaseID:	FBgn0030049	Length:	1001	Species:	Drosophila melanogaster
Sequence 2:	XP_021335997.1	Gene:	mtpap / 563801	ZFINID:	ZDB-GENE-101208-3	Length:	600	Species:	Danio rerio

Alignment Length:	386	Identity:	70/386 - (18%)
Similarity:	138/386 - (35%)	Gaps:	117/386 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   290 AIRNEVVKRIEAVVHSIWPQAVVEIFGSFRTGLFLPTSDIDLV--VLGLWEKLPLR----TLEFE 348
            ::|..|...:..:..:.:|:.::..|||..........|:|::  :.|::.:...:    :||::
Zfish   221 SLRFLVCSLLGDIAGAYFPECIIRPFGSTVNSFGKLGCDVDMILDLDGIYARSQKKGSGLSLEYQ 285

  Fly   349 LVSRGIAEACTVRVLD--------------------KASVPIIKLTDRETQVKVDISFNMQSGVQ 393
            :.:.....|.|..:|.                    :|..||::...:.:..:.|::.|.:..::
Zfish   286 VKTGPSERAVTQSILSVVGKCVDQFGPGCVGVQNILQARCPIVRFAHQPSGFQCDLTANNKVAMK 350

  Fly   394 SAELIKKFKRDYPVLEKLVLVLKQFLLLRDLNEVFTGG-ISSYSLILMCISFLQ-----MHPR-- 450
            |:||:..:....|.:..||..::.:.....:.....|. |:::||.:|.:.|||     |.|.
Zfish   351 SSELLFLYGHLDPRVRHLVFSVRCWARAHSITSSIPGAWITNFSLTVMVVFFLQQRSPAMLPTLD 415

  Fly   451 ----------------------------GIYHDTANLGVLLLEFFELYGRRFNYMKIGISIKNGG 487
                                        .:..:|..|..||.||||.|| .|.:.|..|:|:.|
Zfish   416 RLKELAGPSDKCVIEGNDCTIVSDLSKIALQKNTDTLEKLLQEFFEFYG-NFPFNKASINIRKG- 478

  Fly   488 RYMPKDELQRDMVDGHRPSLLCIEDPLTPGNDIGRSSYGVFQVQQAFKCAYRVLALAVSPLNLLG 552
                |::.:.:....|                          :|..|:..             |.
Zfish   479 ----KEQSKPEAAALH--------------------------IQNPFEAT-------------LN 500

  Fly   553 IDPRVNSI-LGRIIHITDDVIDYREWI---RENFEHLVVVDR--ISPLPTAAPTAYATANG 607
            :...||:. |.|.:.:..:    ..|:   :||.|.......  :||...||..|.:.|:|
Zfish   501 VSKNVNAAQLERFVKLCQE----SAWLFQQKENLEPGSTQSNGSVSPWGFAALLAPSVASG 557

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Trf4-1	NP_001259340.1	NT_PAP_TUTase	291..401	CDD:143392	22/135 (16%)
Trf4-1	NP_001259340.1	PAP_assoc	458..518	CDD:281779	16/59 (27%)
mtpap	XP_021335997.1	RRM_SF	89..>139	CDD:327398
		PAP_assoc	206..>511	CDD:332051	57/334 (17%)
		NT_PAP_TUTase	222..359	CDD:143392	22/136 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5260
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810