Protein Alignment Trf4-1 and MTPAP

DIOPT Version :9

• Sequence 1: NP_001259340.1
• Gene: Trf4-1 / 31795
• FlyBaseID: FBgn0030049
• Length: 1001
• Species: Drosophila melanogaster
• Sequence 2: NP_060579.3
• Gene: MTPAP / 55149
• HGNCID: 25532
• Length: 582
• Species: Homo sapiens
• Alignment Length: 417
• Identity: 80/417 - (19%)
• Similarity: 140/417 - (33%)
• Gaps: 114/417 - (27%)

  Fly   171 STGAGGTGTNSPATTASSTAATTTGPATSMSDTSNNPPQSTTTPASRTNSIYYNPSRKKRPENKA 235
            |.|:...||::|     |||..|..|..|.  ..|...::.|:..||..|....|...|:
Human   123 SIGSLQNGTHTP-----STAMETAIPFRSR--FFNLKLKNQTSERSRVRSSNQLPRSNKQ----- 175

  Fly   236 GGAHYYMNNHMEMIAKYKGEPWRKPDYPYGEGVIGLHEEIEHFYQYVLPTPCEHAIRNEVVKRIE 300
                     ..|::.             |.|.:   .:::....:....|.....:|......||
Human   176 ---------LFELLC-------------YAESI---DDQLNTLLKEFQLTEENTKLRYLTCSLIE 215

  Fly   301 AVVHSIWPQAVVEIFGSFRTGLFLPTSDIDLVVLGLWEKLPLRT--------LEFELVSRGIAEA 357
            .:..:.:|..:|..|||..........|:|: .|.|.|...|..        :||::.:......
Human   216 DMAAAYFPDCIVRPFGSSVNTFGKLGCDLDM-FLDLDETRNLSAHKISGNFLMEFQVKNVPSERI 279

  Fly   358 CTVRVLD--------------------KASVPIIKLTDRETQVKVDISFNMQSGVQSAELIKKFK 402
            .|.::|.                    .|..|:::.:.:.:..:.|::.|.:..:.|:||:..:.
Human   280 ATQKILSVLGECLDHFGPGCVGVQKILNARCPLVRFSHQASGFQCDLTTNNRIALTSSELLYIYG 344

  Fly   403 RDYPVLEKLVLVLKQFLLLRDLNEVFTGG-ISSYSLILMCISFLQMHPRGIY------------- 453
            .....:..||..::.:.....|.....|. |:::||.:|.|.|||.....|.
Human   345 ALDSRVRALVFSVRCWARAHSLTSSIPGAWITNFSLTMMVIFFLQRRSPPILPTLDSLKTLADAE 409

  Fly   454 ----------------------HDTANLGVLLLEFFELYGRRFNYMKIGISIKNGGRYMPKDELQ 496
                                  .:|..|.:||.||||.:| .|.:.|..|:|:.|......|.
Human   410 DKCVIEGNNCTFVRDLSRIKPSQNTETLELLLKEFFEYFG-NFAFDKNSINIRQGREQNKPDS-- 471

  Fly   497 RDMVDGHRPSLLCIEDPLTPGNDIGRS 523
                     |.|.|::|.....:|.::
Human   472 ---------SPLYIQNPFETSLNISKN 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trf4-1	NP_001259340.1	NT_PAP_TUTase	291..401	CDD:143392	25/137 (18%)
		PAP_assoc	458..518	CDD:281779	18/59 (31%)
MTPAP	NP_060579.3	NT_PAP_TUTase	206..344	CDD:143392	25/138 (18%)
		PAP_assoc	440..483	CDD:281779	17/54 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5260
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810