Protein Alignment Trf4-1 and cid14

DIOPT Version :10

• Sequence 1: NP_572490.2
• Gene: Trf4-1 / 31795
• FlyBaseID: FBgn0030049
• Length: 1001
• Species: Drosophila melanogaster
• Sequence 2: NP_001018181.1
• Gene: cid14 / 3361384
• PomBaseID: SPAC12G12.13C
• Length: 684
• Species: Schizosaccharomyces pombe
• Alignment Length: 741
• Identity: 197/741 - (26%)
• Similarity: 318/741 - (42%)
• Gaps: 160/741 - (21%)

  Fly    53 SSSSNSGNNNNNNNNNIINNTIT-----------------NTTNNTGNNSSAKPYLSR---PYSS 97
            |.......|::..:..::||..|                 |..::.|........:|.   ||..
pombe    39 SKRKEKDKNSDAYDEMLLNNNFTLLDQEEPMVEIGSKKSRNDNDSEGIRDKGGVEISNKNDPYIQ 103

  Fly    98 LNRVLNFRADSLEILQQQQQQQQ---------LNGTTQRNSTNINTTSGGSTSSSADS-----TT 148
            ..     :||.||.|::....::         |.|..:|.....|.....:..:::|.     .:
pombe   104 FG-----KADPLEPLEKPDLPEEAIKRGEPTILLGIPKREGRKTNPVHDKAVENNSDFIKFDWNS 163

  Fly   149 NRDNNSPANSSSTNGPGAGTGTSTGAGGTGTNSPATTASSTAATTTGPATSMSDTSNNPPQSTTT 213
            :.|.:|.:|..|.|.                                  .|:..:|.|     ..
pombe   164 DEDEDSVSNDKSKNN----------------------------------ESLKKSSKN-----EI 189

  Fly   214 PA-SRTNSIYYNPSRKKRPENKAGGAHYYMNNHMEMIAKYKGEPWRKPDYPYGEGVIGL-HEEIE 276
            |. .|....:::.:.:|...|:......|..:....       ||.: .|.....|..: |::|.
pombe   190 PGFMRQRGRFFHEANEKSDSNRKRKRQAYELDSQSC-------PWHR-QYKVEREVSRIFHQDIL 246

  Fly   277 HFYQYVLPTPCEHAIRNEVVKRIEAVVHSIWPQAVVEIFGSFRTGLFLPTSDIDLVVLG-----L 336
            ||..|:.|||.|||:|..:|.||...|...||...:.:||||.|.|:|||||:|||::.     .
pombe   247 HFIDYITPTPEEHAVRKTLVSRINQAVLQKWPDVSLYVFGSFETKLYLPTSDLDLVIISPEHHYR 311

  Fly   337 WEKLPLRTLEFELVSRGIAEACTVRVLDKASVPIIKLTDRETQVKVDISFNMQSGVQSAELIKKF 401
            ..|..:..|...|  :.:..|..|:|:..|:|||||..|..|:|.||||||...|:::..::..|
pombe   312 GTKKDMFVLAHHL--KKLKLASEVQVITTANVPIIKFVDPLTKVHVDISFNQPGGLKTCLVVNGF 374

  Fly   402 KRDYPVLEKLVLVLKQFLLLRDLNEVFTGGISSYSLILMCISFLQMHPR---GIYHDTANLGVLL 463
            .:.||.|..||:::|.||.:|.|||||.||:|||:::.:.:||||:|||   |...:..|.||||
pombe   375 MKKYPALRPLVIIIKHFLNMRALNEVFLGGLSSYAIVCLVVSFLQLHPRLSTGSMREEDNFGVLL 439

  Fly   464 LEFFELYGRRFNYMKIGISIKNGGRYMPKDELQRDMVDGHRPSLLCIEDPLTPGNDIGRSSYGVF 528
            |||.||||::|.|..:||::.|||.|..|.::  ..:..::|.||.|:||:...||:.:||.|:.
pombe   440 LEFLELYGKQFYYDAVGIAVHNGGFYFSKKKM--GWLKPNQPYLLSIQDPVDFQNDVSKSSRGLL 502

  Fly   529 QVQQAFKCAYRVL-----ALAVSPLNLLGIDPRVN---SILGRIIHITDDVIDYREWIRENFEHL 585
            :|:..|...:.:|     ||| |.:...|:: ||.   |||..|:.:.       |.:|::.||:
pombe   503 RVKATFANGFDLLTSKLYALA-SRIEREGVN-RVKDFPSILSTILSVD-------EGVRQHREHM 558

  Fly   586 VVVDRISPLPTAAPTAYATANGAPKYVIMPSGAVVQQLYHHPVQVPTAHGHSHAHSHSHGHAHPG 650
            :...:.:|:| ..|.....|..:.....:|...|..|
pombe   559 LKCYKNNPVP-LEPLVEVDALASIDVDKLPLQDVGLQ---------------------------- 594

  Fly   651 AHLCQPYVTGTTVSAVTTTT--TMAVVTVGVSAGGVQQQQQQQNATAHTHSQQQTQNQSQSRHRR 713
                  ||...:.|..|...  .:..|...:...|.:..|:|    |.|.:.:|:.:.|::...:
pombe   595 ------YVEDESDSDETDAAKDDLFKVNESIETNGHENFQKQ----ALTSTGEQSSSNSRANPSK 649

  Fly   714 GSTSSGDDSEDSKDGDVVETTSSAQE 739
            ....|.|||||  :..::|.|:::.|
pombe   650 LFNISSDDSED--EVPIIEDTTASDE 673

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trf4-1	NP_572490.2	TRF4	271..>583	CDD:227585	130/328 (40%)
cid14	NP_001018181.1	TRF4	171..669	CDD:227585	173/598 (29%)