Protein Alignment Trf4-1 and Tent4a

DIOPT Version :10

• Sequence 1: NP_572490.2
• Gene: Trf4-1 / 31795
• FlyBaseID: FBgn0030049
• Length: 1001
• Species: Drosophila melanogaster
• Sequence 2: NP_001402773.1
• Gene: Tent4a / 306672
• RGDID: 1307356
• Length: 784
• Species: Rattus norvegicus
• Alignment Length: 901
• Identity: 326/901 - (36%)
• Similarity: 424/901 - (47%)
• Gaps: 181/901 - (20%)

  Fly     1 MDPFVGWFQKEQEGPSLCTWLKIWETNAQEMGALLNQQLQQATTINGSTSSSSSSSNSGNNNNNN 65
            |||.|.|.|.||:||:...|::||||:             |.....||..:|..
  Rat     1 MDPRVAWIQPEQKGPANALWMQIWETS-------------QGVGRGGSGFASYF----------- 41

  Fly    66 NNNIINNTITNTTNNTGNNSSAKPYLSRP------------------YSSLNRVLNFRADSLEIL 112
               .:|:...:|....|....|.|....|                  ..:|...|...||....|
  Rat    42 ---CLNSPALDTAAAPGAAGRAAPAAGGPGPAPAASSPPPAPGPAALPPALLTALGPAADGARRL 103

  Fly   113 QQQQQQQQLNGTTQRNSTNINTTSGGSTSSSADSTTNRDNNSPANSSSTNGPGAGTGTSTGAGGT 177
            .:..                :.:|..|:||:|:|.|    .||..|||::     :.||.|..|:
  Rat   104 HKSP----------------SLSSSSSSSSNAESGT----ESPGCSSSSS-----SSTSLGRAGS 143

  Fly   178 GTN--SPATTASSTAATTTGPATSMSDTSNNPPQSTTTPASRTNSIYYNPSRKKRPENKAG--GA 238
            |..  |.|..|:.......||.     .:.:|||.           .::|.|:|| ||||.  |.
  Rat   144 GRTFFSFADGAAHAHPGPRGPT-----PAGSPPQH-----------QFHPGRRKR-ENKASTYGL 191

  Fly   239 HYYMNNHMEMI----------AKYKGEPWRKPDYPYGEGVIGLHEEIEHFYQYVLPTPCEHAIRN 293
            :|.::......          |...|.||:  ...|..|:.||||||..||.::.|.|.|.|:|.
  Rat   192 NYLLSGSRAATLSGGGGPGAQAARPGTPWK--SRAYSPGIQGLHEEIIDFYNFMSPCPEEAAMRR 254

  Fly   294 EVVKRIEAVVHSIWPQAVVEIFGSFRTGLFLPTSDIDLVVLGLWEKLPLRTLEFELVSRGIAEAC 358
            |||||||.||..:||.|.|:|||||.|||:||||||||||.|.||:.||:.||..|....:||.|
  Rat   255 EVVKRIETVVKDLWPSADVQIFGSFSTGLYLPTSDIDLVVFGKWERPPLQLLEQALRKHNVAEPC 319

  Fly   359 TVRVLDKASVPIIKLTDRETQVKVDISFNMQSGVQSAELIKKFKRDYPVLEKLVLVLKQFLLLRD 423
            :::|||||:||||||||:||:|||||||||::||::||.||.:.:.|.:|..|:||||||||.||
  Rat   320 SIKVLDKATVPIIKLTDQETEVKVDISFNMETGVRAAEFIKNYMKKYSLLPYLILVLKQFLLQRD 384

  Fly   424 LNEVFTGGISSYSLILMCISFLQMHPR-GIYHDTANLGVLLLEFFELYGRRFNYMKIGISIKNGG 487
            |||||||||||||||||.|||||:||| .......|||:||:||||||||.|||:|.||.||.||
  Rat   385 LNEVFTGGISSYSLILMAISFLQLHPRIDARRADENLGMLLVEFFELYGRNFNYLKTGIRIKEGG 449

  Fly   488 RYMPKDELQRDMVDGHRPSLLCIEDPLTPGNDIGRSSYGVFQVQQAFKCAYRVLALAVSPLNLLG 552
            .|:.|:|:.:.|..|:|||:|||||||.||||:||||||..||:|.|..||.||:.|||||....
  Rat   450 AYIAKEEIMKAMTSGYRPSMLCIEDPLLPGNDVGRSSYGAMQVKQVFDYAYIVLSHAVSPLARSY 514

  Fly   553 IDPRVNSILGRIIHITDDVIDYREWIRENFEHLVVVDRISPLP-----TAAPTAYATANGAPKYV 612
            .:....|.|||||.:|.:|||||.||:|.:.     .||.|.|     ........|.||.....
  Rat   515 PNRDSESTLGRIIKVTQEVIDYRRWIKEKWG-----SRIVPSPDLDNRIKIKERVTTCNGEQMQS 574

  Fly   613 IMPSGAVVQQL---YHHPVQVPTAHGHSHAHSHSHGHAHPGAHLC-QPYVTGTTVSAVTTTTTMA 673
            ..||....|:|   ...|..:.:....|...|.|..........| .|.|...::.|  .||.||
  Rat   575 REPSSPYSQRLTLSLSSPQLLSSGSSASSVSSLSGSDIDSDTPPCTTPSVYQFSLQA--PTTLMA 637

  Fly   674 VVTVGVSAGGVQQQQQQQNATAHTHSQQQTQNQSQSRHRRGSTSSGDDSEDSKDGDVVETTSSAQ 738
            .:...:.....:.|.........|     |.||::
  Rat   638 GLPTALPVPSSKPQPAASRTLIMT-----TNNQTR------------------------------ 667

  Fly   739 EVVDIALSTPN-GLANMSMPMPVHAVGMPASNSWSGNGNGNG----NSSSSTGSSPEIAHIAAQE 798
                :.:..|. |:|    |:|....|:..:.|.....|...    ::|.:..|||.:.|.....
  Rat   668 ----VTIPPPTLGVA----PVPCRQAGVDGTTSLKAVHNVTSPAIPSASPNPLSSPHLYHKQHNG 724

  Fly   799 MDPELEDQQQQQQHQETSGGNGFIRPGDVGTGSNRGGGDGSGGRNYN----QRNNH 850
            |...::.     .|..|.|| |:   ..||:|:.|......|...||    :|..|
  Rat   725 MKLSMKG-----SHNHTQGG-GY---SSVGSGAVRPPVGNRGHHQYNRTGWRRKKH 771

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trf4-1	NP_572490.2	TRF4	271..>583	CDD:227585	198/312 (63%)
Tent4a	NP_001402773.1	TRF4	232..>537	CDD:227585	193/304 (63%)
		KLF8_12_N	<620..>719	CDD:424081	24/143 (17%)