Protein Alignment Trf4-1 and Tent4b

DIOPT Version :9

• Sequence 1: NP_001259340.1
• Gene: Trf4-1 / 31795
• FlyBaseID: FBgn0030049
• Length: 1001
• Species: Drosophila melanogaster
• Sequence 2: NP_001359262.1
• Gene: Tent4b / 214627
• MGIID: 1917820
• Length: 700
• Species: Mus musculus
• Alignment Length: 957
• Identity: 311/957 - (32%)
• Similarity: 420/957 - (43%)
• Gaps: 310/957 - (32%)

  Fly     1 MDPFVGWFQKEQEGPSLCTWLKIWETNAQEMGALLNQQLQQATTINGSTSSSSSSSNSGNNNNNN 65
            |||.:.|||.||.|||...|::||||.........|....       |:.:||:|..||
Mouse     1 MDPRIAWFQPEQLGPSNSLWMQIWETTQGLRNLYFNHHCH-------SSGASSASGGSG------ 52

  Fly    66 NNNIINNTITNTTNNTGNNSSAKPYLSRPYSSLNRVLNFRADSLEILQQQQQQQQLNGTTQRNST 130
                         :..|:.....|..:..:.|..|.|...|...|               ||:..
Mouse    53 -------------SGPGSPGGTAPAPAGMFRSGERPLGGLAVPAE---------------QRDFL 89

  Fly   131 NINTTSGGSTSSSADSTTNRDNNSPA--NSSSTNGPGAGTGTSTGAGGTGTNSPATTASSTAATT 193
            .:.||:           .|.:::.||  ...::.||.|              ||..:|.|:..
Mouse    90 PLETTN-----------NNNNHHQPAAWARRASAGPSA--------------SPVPSAPSSPR-- 127

  Fly   194 TGPATSMSDTSNNPPQSTTTPASRTNSIYYNPSRKKRPENKAG--GAHYYMNNHMEMIAK----- 251
              ||.::      |...:|.|||       ..|.|::.:|||.  |.:|.:.......|.
Mouse   128 --PAAAL------PASESTDPAS-------GSSNKRKRDNKASTYGLNYSLLQPSGGRAAGGGRA 177

  Fly   252 ------YKGEPWRKPDYPYGEGVIGLHEEIEHFYQYVLPTPCEHAIRNEVVKRIEAVVHSIWPQA 310
                  |.|.||::.:  |.:||:||||||..||:|:.|.|.|..:|.|||.|||:|:..:||.|
Mouse   178 DGGGGVYSGTPWKRRN--YNQGVVGLHEEISDFYEYMSPRPEEEKMRMEVVSRIESVIKELWPSA 240

  Fly   311 VVEIFGSFRTGLFLPTSDIDLVVLGLWEKLPLRTLEFELVSRGIAEACTVRVLDKASVPIIKLTD 375
            .|:|||||:|||:||||||||||.|.||.|||.|||..|....:|:..:|:|||||:||||||||
Mouse   241 DVQIFGSFKTGLYLPTSDIDLVVFGKWENLPLWTLEEALRKHKVADEDSVKVLDKATVPIIKLTD 305

  Fly   376 RETQVKVDISFNMQSGVQSAELIKKFKRDYPVLEKLVLVLKQFLLLRDLNEVFTGGISSYSLILM 440
            ..|:||||||||:|:||::|:|||.|.:.||||..||||||||||.|||||||||||.||||.||
Mouse   306 SFTEVKVDISFNVQNGVRAADLIKDFTKKYPVLPYLVLVLKQFLLQRDLNEVFTGGIGSYSLFLM 370

  Fly   441 CISFLQMHPRGIYHD----TANLGVLLLEFFELYGRRFNYMKIGISIKNGGRYMPKDELQRDMVD 501
            .:||||:|||   .|    ..|.||||:||||||||.|||:|.||.||:||.|:.|||:|::|:|
Mouse   371 AVSFLQLHPR---EDACIPNTNYGVLLIEFFELYGRHFNYLKTGIRIKDGGSYVAKDEVQKNMLD 432

  Fly   502 GHRPSLLCIEDPLTPGNDIGRSSYGVFQVQQAFKCAYRVLALAVSPLNLLGIDPRVNSILGRIIH 566
            |:|||:|.|||||.||||:||||||..||:|||..||.||:.||||:.....:....|||||||.
Mouse   433 GYRPSMLYIEDPLQPGNDVGRSSYGAMQVKQAFDYAYVVLSHAVSPIAKYYPNNETESILGRIIR 497

  Fly   567 ITDDVIDYREWIRENFEHLVVVDRISPLPTAAPTAYATANGAPKYVIMPSGAVVQQLYHHPVQVP 631
            :||:|..||:||.:.:                                       .|.:.|
Mouse   498 VTDEVATYRDWISKQW---------------------------------------GLQNRP---- 519

  Fly   632 TAHGHSHAHSHSHGHAHPGAHLCQPYVTGTTVSAVTTTTTMAVVTVGVSAGGVQQQQQQQNATAH 696
                                   :|...|..|:.:..|                ||..:.|
Mouse   520 -----------------------EPSCNGNGVTLIVDT----------------QQLDKCN---- 541

  Fly   697 THSQQQTQNQSQSRHRRGSTSSGDDSEDSKDGDVVETTSSAQEVVDIALSTPNGLANMSMPMPVH 761
                   .|.|:.:...|...|                                  |.|.|:..|
Mouse   542 -------NNLSEEKEALGKCRS----------------------------------NASEPLSKH 565

  Fly   762 AVGMPASNSWSGNGNGNGNSSSSTGSS---------------------PEIAHIAAQEMDPELED 805
            :         |.:.:|..:|||:|.||                     |.:..:.:|::..|:..
Mouse   566 S---------SNSSSGPVSSSSATQSSSSDVDSDATPCKTPKQLLCRPPTVTRVGSQDVSLEVSQ 621

  Fly   806 QQQQQQHQETSGGNGFIRPGDVGTGSNRGGGDGSGGRNYNQRNNHNSSGYYHQQYYVPPPMQQQL 870
            ...:.|..:|:                            |..||.|.|.:...:.:
Mouse   622 AVGKMQSTQTT----------------------------NTPNNANKSQHGSARLF--------- 649

  Fly   871 SKSNSSSNYHQQHHHSH-------SHGNHSHRQQHHHQQQHHHQQRP 910
              .:||..:......||       .|...|:.|.:|.:::.|.:..|
Mouse   650 --RSSSKGFQGTAQTSHGALMTSKQHQGKSNTQYYHGKKRRHKRDAP 694

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trf4-1	NP_001259340.1	NT_PAP_TUTase	291..401	CDD:143392	71/109 (65%)
		PAP_assoc	458..518	CDD:281779	41/59 (69%)
Tent4b	NP_001359262.1	TRF4	201..>473	CDD:227585	180/274 (66%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167830720
Domainoid	1	1.000	136	1.000	Domainoid score	I4907
eggNOG	1	0.900	-	-		E1_COG5260
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002099
OrthoInspector	1	1.000	-	-		otm42852
orthoMCL	1	0.900	-	-		OOG6_101092
Panther	1	1.100	-	-	O	PTHR23092
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2219
SonicParanoid	1	1.000	-	-		X1551
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.730