Protein Alignment Trf4-1 and gldr-2

DIOPT Version :9

• Sequence 1: NP_001259340.1
• Gene: Trf4-1 / 31795
• FlyBaseID: FBgn0030049
• Length: 1001
• Species: Drosophila melanogaster
• Sequence 2: NP_001021434.1
• Gene: gldr-2 / 173373
• WormBaseID: WBGene00009284
• Length: 808
• Species: Caenorhabditis elegans
• Alignment Length: 657
• Identity: 118/657 - (17%)
• Similarity: 226/657 - (34%)
• Gaps: 242/657 - (36%)

  Fly     2 DPFVGWFQKEQEGPSLCTWLKIWETNAQEMGALLNQQLQQATTINGSTSSSSSS------SNSGN 60
            |.:.|..|:...||:     :::....:.     ||.:||....|.:.:|....      ..:..
 Worm   260 DTYFGECQQLLHGPT-----EVYCARPES-----NQFVQQYEEANSTEASEDEDKEAVPMKRARV 314

  Fly    61 NNNNNNNNIINNTITNTTNNTGNNSSAKPYLSRPYSSLNRVLN--------FRADSLEILQQQQQ 117
            :...:::::|   :.|.|.::|  .|.|..:|.....:..:::        .:.|.||.|:....
 Worm   315 DIEEDDDDVI---VLNMTTSSG--VSDKKDVSGSEDEIGDIVDEWDANDEEEKTDELEELEDDDI 374

  Fly   118 Q-----QQLNGTTQRNSTNINTTSGGSTSSSADSTTNRDNNSPANSSSTNGPGAGTGTSTGAGGT 177
            |     .|.||..:.:||.|:..:..|:|         |.|...|...|:
 Worm   375 QIIEAGDQGNGVEEVSSTVISVETPNSSS---------DENKIYNGHQTH--------------- 415

  Fly   178 GTNSPATTASSTAATTTGPATSMSDTSNNPPQSTTTPASRTNSIYYNPSRKKRPENKAGGAHYYM 242
                                    .......|......:||..:..|       |..||....::
 Worm   416 ------------------------QIFREVRQLPVNYQARTIGVVLN-------ERIAGSVEKFV 449

  Fly   243 N-------NHMEMIAK-----YKGEPWRKPDYPYGEGVIGLHEEIEHFYQYVLPTPCEHAIRNEV 295
            |       |.::.::|     |.|.  .:||:.:
 Worm   450 NSITKKSFNSVKQLSKLAWDHYLGN--AQPDFVF------------------------------- 481

  Fly   296 VKRIEA------VVHSIWPQAVVEI--FGSFRTGLFLPTSDIDLVVLGLWEKLPLRTLEFELVSR 352
            :|::||      .:..::|...:::  .||...|.....||:||.:.     .|....:
 Worm   482 LKKMEARQKLFSEIKKLFPDTEIKLQTTGSTVNGCGSFNSDMDLCLC-----FPTNGYK------ 535

  Fly   353 GIAEAC------------TVRVLDK----------------------ASVPIIK--LTDRETQVK 381
              .:.|            .:|.:||                      |.|||:|  |......::
 Worm   536 --GQVCDDFHCDRNYSTKILRKIDKAFRRSHWSHPLKKIIKTMQLVPAKVPIVKMILNGEFDGIE 598

  Fly   382 VDISFNMQSGVQSAELIKKFKRDYPVLEKLVLVLKQFLLLRDLNEVFTGGISSYSLILMCISFLQ 446
            |||:.|..:|:.::.||..:......|..|.|::|.:.::..:|....|.::||:.||:.:.:||
 Worm   599 VDINVNNIAGIYNSHLIHYYSLTDARLPALALLVKHWAMVTGINNAQDGFLNSYTTILLVVHYLQ 663

  Fly   447 -------------MHPRG-----------IYHDTA-----------NLGVLLLEFFELYGRRFNY 476
                         :.|..           ::.|.|           :||.||:.||:.| ..|::
 Worm   664 CGVTPAVIPNLQYLFPHKFDRKLPLNELLLFGDIADKLPTSPPNTWSLGELLIGFFQYY-NEFDF 727

  Fly   477 MKIGISIKNGGRYMPKDELQRDMVDGHRPSLLCIEDPLTPGN------DIGRSSYGVFQVQQAFK 535
            ...|.||:: |:.:|::.|.||:::    |.:.:|:|....|      |:....    .::.||:
 Worm   728 TNFGFSIRS-GQVIPRENLPRDLIN----SPIVVEEPFDAINTARTVRDVSHMK----SIKSAFR 783

  Fly   536 CAYRVLA 542
            ||.::::
 Worm   784 CAVQIIS 790

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trf4-1	NP_001259340.1	NT_PAP_TUTase	291..401	CDD:143392	29/153 (19%)
		PAP_assoc	458..518	CDD:281779	19/59 (32%)
gldr-2	NP_001021434.1	TRF4	483..>799	CDD:227585	69/331 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910