Protein Alignment Trf4-1 and gld-4

DIOPT Version :10

• Sequence 1: NP_572490.2
• Gene: Trf4-1 / 31795
• FlyBaseID: FBgn0030049
• Length: 1001
• Species: Drosophila melanogaster
• Sequence 2: NP_492446.3
• Gene: gld-4 / 172735
• WormBaseID: WBGene00014115
• Length: 845
• Species: Caenorhabditis elegans
• Alignment Length: 904
• Identity: 232/904 - (25%)
• Similarity: 371/904 - (41%)
• Gaps: 243/904 - (26%)

  Fly   180 NSPATTASSTAATTTGPATSMSDTSNNPPQSTTTPASRTNSIYYNPSRKKRPENKAGGAHYYMNN 244
            |..:..:||...:|:.|.:|:..|.|:...:|....|::..   .||..:..:::.....|  ::
 Worm     2 NEDSRLSSSQQPSTSTPRSSIPSTMNSDEPNTCRRLSQSQE---QPSTSRTCKSETPEFGY--SD 61

  Fly   245 HMEMIAKYKGEPWRKPDYPYGEGVIGLHEEIEHFYQYVLPTPCEHAIRNEVVKRIEAVVHSIWPQ 309
            .:..      .|||:.  .||..:.||||||...|.::.|...|..:|.:|.:::...|...|.|
 Worm    62 SLPF------APWRRK--RYGLNIQGLHEEIVDMYHWIKPNEIESRLRTKVFEKVRDSVLRRWKQ 118

  Fly   310 AVVEI--FGSFRTGLFLPTSDIDLVV--------LGLWEKLPLRTLEFELVSRGIAEACTVRVLD 364
            ..::|  |||.||.|||||||||::|        .|.|.....|.||.:    .|||  :|.|..
 Worm   119 KTIKISMFGSLRTNLFLPTSDIDVLVECDDWVGTPGDWLAETARGLEAD----NIAE--SVMVYG 177

  Fly   365 KASVPIIKLTDRETQVKVDISFNMQSGVQSAELIKKFKRDYPVLEKLVLVLKQFLLLRDLNEVFT 429
            .|.|||:|:.||:|::.:|||||...||::|..|.|.|.::|::|.|||:|||||..|:||:.||
 Worm   178 GAFVPIVKMVDRDTRLSIDISFNTVQGVRAASYIAKVKEEFPLIEPLVLLLKQFLHYRNLNQTFT 242

  Fly   430 GGISSYSLILMCISFLQ-----MHPRGIYHDTANLGVLLLEFFELYGRRFNYMKIGIS------- 482
            ||:|||.|:|:.::|.|     |..|.||....|||.|||.|.|||...||:.::|||
 Worm   243 GGLSSYGLVLLLVNFFQLYALNMRSRTIYDRGVNLGHLLLRFLELYSLEFNFEEMGISPGQCCYI 307

  Fly   483 --IKNGGRYMPKDELQRDMVDGHR---PSLLCIEDPLTPGNDIGRSSYGVFQVQQAFKCAYRVLA 542
              ..:|.||            ||:   |..|.:||||...||:|||:|....:..||..|:::|.
 Worm   308 PKSASGARY------------GHKQAQPGNLALEDPLLTANDVGRSTYNFSSIANAFGQAFQILL 360

  Fly   543 LAVS-----PLNLLGIDPRVNSILGRIIHITDDVIDYREWIRENFEHLVVVDRISPLP-TAAPTA 601
            :||:     ..|.:.:.....|:|..|:..|...:.||.|:         :..:..:| ..||.:
 Worm   361 VAVTLRERKGKNHVAMRAYKGSLLHLIMPFTSKELTYRNWL---------MSGVLSMPGQEAPAS 416

  Fly   602 YATANGAPKYVIMPSGAVVQQLYHHPVQVPTAHGHSHAHSHSHGHAHPGAHLCQPYVTGTTVSAV 666
            |.                :.||::..|.                   |...|.: |.......|.
 Worm   417 YD----------------LNQLHNTLVS-------------------PMVDLSR-YAWLRKAPAK 445

  Fly   667 TTTTTMAVVTVGVSAGGVQQQQQQQNATAHTHSQQQTQNQSQSRHRRGSTSSGDDSEDSKDGDVV 731
            ........:|:...|...|...||        .::|...|::::.......:.||::  |:.::|
 Worm   446 AEKRDSRPLTIVNPADDRQTLAQQ--------LKKQILEQTEAKKSLEKMPACDDNK--KEEELV 500

  Fly   732 ETTSSAQEVV--------------DIALSTPNGLANMSMPMPVHAVGMPASNSWSGNGNGNGNSS 782
            .|..:..|:.              |:.|:.|        |:|.....:              |:|
 Worm   501 ATRETDVELEAEDTESEGHHNGENDLILTGP--------PLPTSTQSV--------------NTS 543

  Fly   783 SSTGSSPEIAHIAAQEMDPELEDQQQQQQHQETSGGNGFIRPG---DVGTGSNRGGGDGSGGRNY 844
            ::..::..|:         |.||...               ||   .:|..|:....|
 Worm   544 ATVSTAASIS---------EREDTDS---------------PGLSSSMGNQSSEEDED------- 577

  Fly   845 NQRNNHNSSGYYHQ------QYYVPPPMQQQLSKSNSSSNYHQQ-HHHSHSHGNHSH------RQ 896
            |..||.|:|....|      :....|..:.:.:::.|......| |.:.:|:...|.      ..
 Worm   578 NGINNRNNSAVPVQFKKPFNEVVAQPARESKRTQTTSEDKMQDQFHFNGYSYPPPSRYAAGTAAP 642

  Fly   897 QHHHQQQHHHQQRP--QHLRVG--GGNRYQKSLGGSPIISAGNASNSS----------SNC---- 943
            .|.|:..|..:|||  ::|..|  |.:.|......:.|.....||::|          .||
 Worm   643 SHKHRNAHPQRQRPSIRNLSQGSDGSDEYNVESWNNNIRQGRRASSNSPSPSRQQTNTRNCGPTN 707

  Fly   944 ----------SNSSSSSGSNNSRLPPLRGTLVNSSSAISIIS--ISSESSIASSSSSSS 990
                      :.:|:..|||||           |...|::.:  :..:|||.:|:::|:
 Worm   708 NIPYDSFRSQNKNSTLDGSNNS-----------SEEPITMYADVVKKKSSITTSTNTST 755

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trf4-1	NP_572490.2	TRF4	271..>583	CDD:227585	132/343 (38%)
gld-4	NP_492446.3	TRF4	80..>381	CDD:227585	125/318 (39%)