Protein Alignment Trf4-1 and TENT2

DIOPT Version :9

• Sequence 1: NP_001259340.1
• Gene: Trf4-1 / 31795
• FlyBaseID: FBgn0030049
• Length: 1001
• Species: Drosophila melanogaster
• Sequence 2: NP_001336478.1
• Gene: TENT2 / 167153
• HGNCID: 26776
• Length: 509
• Species: Homo sapiens
• Alignment Length: 455
• Identity: 102/455 - (22%)
• Similarity: 169/455 - (37%)
• Gaps: 149/455 - (32%)

  Fly   180 NSPATTASSTAATTTGPATSMSDTSNNPPQSTTTPASRTNSIYYNPSRKKRPENK----AGGAHY 240
            |:..:.|.|....|.|        :.:|.|::.:|..|        .||:..:.|    .|....
Human    44 NADLSRAVSLQQLTYG--------NVSPIQTSASPLFR--------GRKRLSDEKNLPLDGKRQR 92

  Fly   241 YMNNHME-----MIAKYKGEPWRK------------PDY-----PYGE------GVIGLHEEIEH 277
            :.:.|.|     .|....||  |:            ||.     |:.|      ..|.|.|..:.
Human    93 FHSPHQEPTVVNQIVPLSGE--RRYSMPPLFHTHYVPDIVRCVPPFREIAFLEPREITLPEAKDK 155

  Fly   278 FYQYVLP--TPCEHAI----RNEVVK-RIEAVVHSIWPQAVVEIFGSFRTGLFLPTSDIDLV--- 332
            ..|.:|.  ..|:..|    :.|:.: :::..:..::||:.:.:.||...|....:||.||.
Human   156 LSQQILELFETCQQQISDLKKKELCRTQLQREIQLLFPQSRLFLVGSSLNGFGTRSSDGDLCLVV 220

  Fly   333 -----------------VLGLWEK-------------------LPLRTLEFELVSRGIAEACTVR 361
                             :|.|..|                   :.|..:...|.|.|..|.   .
Human   221 KEEPCFFQVNQKTEARHILTLVHKHFCTRLCKSDMPQVCMSPDVTLLKMPLTLSSAGYIER---P 282

  Fly   362 VLDKASVPIIKLTDRETQVKVDISFNMQSGVQSAELIKKFKRDYPVLEK----LVLVLKQFLLLR 422
            .|.:|.|||:|..|:.:.|:.|::.|...|:::..|:    |.|..||.    ||||:|::....
Human   283 QLIRAKVPIVKFRDKVSCVEFDLNVNNIVGIRNTFLL----RTYAYLENRVRPLVLVIKKWASHH 343

  Fly   423 DLNEVFTGGISSYSLILMCISFLQMHP-------RGIYHDT------------------------ 456
            .:|:...|.:|||||:||.:.:||..|       :.||.::
Human   344 QINDASRGTLSSYSLVLMVLHYLQTLPEPILPSLQKIYPESFSPAIQLHLVHQAPCNVPPYLSKN 408

  Fly   457 -ANLGVLLLEFFELYGRRFNYMKIGISIKNGGRYMPKDELQRDMVDG--HRPSLLCIEDPLTPGN 518
             :|||.|||.|.:.|...|::....||::. .:.:|:.       ||  .|...:|:|:|....|
Human   409 ESNLGDLLLGFLKYYATEFDWNSQMISVRE-AKAIPRP-------DGIEWRNKYICVEEPFDGTN 465

  Fly   519  518
            Human   466  465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trf4-1	NP_001259340.1	NT_PAP_TUTase	291..401	CDD:143392	31/153 (20%)
		PAP_assoc	458..518	CDD:281779	18/61 (30%)
TENT2	NP_001336478.1	TRF4	154..>493	CDD:227585	76/327 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5260
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810