DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Trf4-1 and C53A5.17

DIOPT Version :9

Sequence 1:	NP_001259340.1	Gene:	Trf4-1 / 31795	FlyBaseID:	FBgn0030049	Length:	1001	Species:	Drosophila melanogaster
Sequence 2:	NP_001256592.1	Gene:	C53A5.17 / 13216595	WormBaseID:	WBGene00194707	Length:	474	Species:	Caenorhabditis elegans

Alignment Length:	170	Identity:	37/170 - (21%)
Similarity:	67/170 - (39%)	Gaps:	47/170 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   469 LYGRRFNYMK-IGISIKNGGRYM--PKDELQRDMVDGHRPSLLCIE-------DPLTPGNDIGRS 523
            |.|.:...:| :..|.|:|.:|:  ..|::|.|........||..|       |..|...|:
Worm    60 LIGHKLKPLKNLVDSEKDGKKYLVFHPDKVQEDETRFKILELLKRELGNEKLLDWTTLSKDL--- 121

  Fly   524 SYGVFQVQQAFKCAYRVLALAVSPLNLLGIDPRVNSILGRIIH--ITDDVIDYREWIRENFEHLV 586
            ::..:..:..||        ||.|   :|||....:..|.|||  ..|:::.:|..|.|     |
Worm   122 TFENWDAKSIFK--------AVLP---VGIDYSSYTQTGHIIHCNFADEILPFRFIIAE-----V 170

  Fly   587 VVDRISPLPTAAPTAYATANGAPKYVIMPSGAVVQQLYHH 626
            ::|:::...|                ::..|.::..:|.:
Worm   171 LLDKVNNCKT----------------VVQKGNIITNVYRN 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Trf4-1	NP_001259340.1	NT_PAP_TUTase	291..401	CDD:143392
Trf4-1	NP_001259340.1	PAP_assoc	458..518	CDD:281779	15/58 (26%)
C53A5.17	NP_001256592.1	Met_10	144..363	CDD:280612	13/72 (18%)
C53A5.17	NP_001256592.1	AdoMet_MTases	268..>311	CDD:302624
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5260
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900