Protein Alignment Trf4-1 and LOC1281604

DIOPT Version :10

• Sequence 1: NP_572490.2
• Gene: Trf4-1 / 31795
• FlyBaseID: FBgn0030049
• Length: 1001
• Species: Drosophila melanogaster
• Sequence 2: XP_321547.4
• Gene: LOC1281604 / 1281604
• VectorBaseID: AGAMI1_009307
• Length: 1041
• Species: Anopheles gambiae
• Alignment Length: 1141
• Identity: 431/1141 - (37%)
• Similarity: 553/1141 - (48%)
• Gaps: 311/1141 - (27%)

  Fly     1 MDPFVGWFQKEQEGPSLCTWLKIWETNAQEMGALLNQQLQQATTINGSTSSSSS----------- 54
            |||.|.|:|:||:||:..||::|||:|:...|.|      .|....||.:....
Mosquito     1 MDPAVAWYQEEQDGPAKHTWMRIWESNSDLYGPL------HANYGPGSNNGQEGLKGPGGARGEL 59

  Fly    55 ------SSNSGNNNNNNNNNIINN--------------TITNTTNNTGNNSSAKPYLSRPYSSLN 99
                  ..|:||:.||||||.:.|              |..|..||.|:|:.|    :....|.|
Mosquito    60 KQFDLPLGNTGNSGNNNNNNGVGNHQQQPSPVNEGTGKTNNNNNNNNGSNAGA----TVNSGSSN 120

  Fly   100 RVLNFRADSLEILQQQQQQQQLNGTTQRNSTNINTTSGGSTSSSADSTTNRDNNSPANSSSTNGP 164
            ..|:             ....|||:...::|...||: .:...:.:..:|.:|||.::||..|..
Mosquito   121 AALS-------------NSSVLNGSNSGSATTTTTTT-PTNPGNGNGGSNNNNNSNSSSSCNNHV 171

  Fly   165 GAGT---GTSTGAG----GTGTNSPATTASSTAATTTGPATSMSDTSNNPPQSTTTPASRTNSIY 222
            .:.|   ||:.|.|    |.|||...........|.||.....|...|
Mosquito   172 SSNTNNNGTTNGGGELTTGGGTNGCTKAGGGGGGTGTGGGLVSSSEKN----------------- 219

  Fly   223 YNPSRKK----RPENKAGGAHYYMNNHME-MIAKYKGEPWRKPDYPYGEGVIGLHEEIEHFYQYV 282
            |||.|||    ..||||  :.:.||...: :...:.|.|||.|::.||.|:||||:|||.||.::
Mosquito   220 YNPVRKKLGSMMTENKA--STFNMNKQQQRLTGVHGGCPWRPPNFKYGRGIIGLHQEIEQFYAHM 282

  Fly   283 LPTPCEHAIRNEVVKRIEAVVHSIWPQAVVEIFGSFRTGLFLPTSDIDLVVLGLWEKLPLRTLEF 347
            :.||.|||:|..||.|||.:|.::||.|.||:||||||||:||||||||||:|.|..|||||||.
Mosquito   283 IATPTEHALRVMVVSRIEKIVQNLWPSARVEMFGSFRTGLYLPTSDIDLVVIGQWTMLPLRTLEM 347

  Fly   348 ELVSRGIAEACTVRVLDKASVPIIKLTDRETQVKVDISFNMQSGVQSAELIKKFKRDYPVLEKLV 412
            ||:|:||||..:|||||||||||:|||||:|||||||||||:||||||:|||.|||:||||||||
Mosquito   348 ELISQGIAEPNSVRVLDKASVPIVKLTDRQTQVKVDISFNMESGVQSAKLIKGFKREYPVLEKLV 412

  Fly   413 LVLKQFLLLRDLNEVFTGGISSYSLILMCISFLQMH---PRGIYHDTANLGVLLLEFFELYGRRF 474
            ||||||||.|||||||||||||||||||||||||.|   |..    .:||||||:||||||||:|
Mosquito   413 LVLKQFLLQRDLNEVFTGGISSYSLILMCISFLQQHHQKPNA----CSNLGVLLIEFFELYGRKF 473

  Fly   475 NYMKIGISIKNGGRYMPKDELQRDMVDGHRPSLLCIEDPLTPGNDIGRSSYGVFQVQQAFKCAYR 539
            ||||||||:|: |||:||:||||:|:||||||||||||||||||||||||||...|:|||:.||.
Mosquito   474 NYMKIGISVKS-GRYIPKEELQREMIDGHRPSLLCIEDPLTPGNDIGRSSYGALHVKQAFEYAYI 537

  Fly   540 VLALAVSPLNLLGIDPRVNSILGRIIHITDDVIDYREWIRENFEHLVVVDRISPLPTAAPTAYAT 604
            ||..||.||:....|....|||||||.:||:||:||:||::.||
Mosquito   538 VLVQAVLPLDKNLNDCNRQSILGRIIRVTDEVIEYRKWIKDTFE--------------------- 581

  Fly   605 ANGAPKYVIMPSGAVVQQLYHHPVQVPTAHGHSHAHSHSHGHAHPGAHLCQPYVTGTTVSAVTTT 669
                .|.:..||                                    |.||          .||
Mosquito   582 ----DKLIRQPS------------------------------------LQQP----------LTT 596

  Fly   670 TTMAVVTVGVSAGGVQQQQQ-----QQNATAHTHSQQQTQNQSQSRHRRGSTSSGDDSEDSKDGD 729
            ||:.:....:.....|||||     ||.|..|.|.||..:   |..|||.||||.:.||:|.|.|
Mosquito   597 TTVLLSDHYLPLQQQQQQQQARHLPQQQAIHHIHQQQYPR---QVIHRRPSTSSVELSEESMDSD 658

  Fly   730 ----------VVETTSSAQEVVDIALS-TPNGLANMSMPMPVHAVGMPASNSWSGNGNGNGNSSS 783
                      :...|..     ||:.| :..||...|.|:.:|.:    ......||........
Mosquito   659 GGGASGDFHCLPSATGR-----DISPSASAAGLTTRSPPIELHEL----QQQQQQNGGPTATIMM 714

  Fly   784 STGSSPEIAH-IAAQE-----MDPELEDQQQQQQHQETSGGNGFIRPGDVGTGSNRGGGDGSGGR 842
            .:.:.|...| :..:|     |.......|||||.|.::..||.:              |.....
Mosquito   715 ISTAGPHHPHDLLIEENNMLNMTHHQHQHQQQQQQQLSADPNGIV--------------DAPQVI 765

  Fly   843 NYNQRNNHNSSGYYHQQYYVPPPMQQQLSKSNSSSNYHQQHHHSH-------------------- 887
            :||..||..         .||.|.|||          .|||||.|
Mosquito   766 SYNNMNNRR---------IVPSPNQQQ----------QQQHHHHHLQQQQQIVGKNTLYSRNSSE 811

  Fly   888 ------SHGNHS----HRQQHHHQQQHH-------------HQQRPQHL--RVGGGNRYQKSLGG 927
                  :.||:|    :..|.|.|||||             |..:.:.|  ..||..:...|...
Mosquito   812 RMLPSGATGNNSTNSAYSMQSHQQQQHHQPSAVSNSNGLVRHNSKSRRLITTTGGMLKMPPSSNS 876

  Fly   928 SP-------IISAGNASNSSSNCS-----------------NSSSSSGSNNSRLPPLRGTLVNSS 968
            ||       ::.:|.|||:||:.:                 .|:|...:....||.|....:..:
Mosquito   877 SPSSYPSPDVVISGLASNNSSSSNLVAAGMVINDENNLHYHRSASPKATVAGGLPLLPSNALAGN 941

  Fly   969 SAISIISI----------SSESSIASSSSSSSRSGQ 994
            :.:.:..:          .:.|:|:|:::|||.||:
Mosquito   942 NGVIMTGVGGGGGGGSAGGAGSTISSNTNSSSSSGK 977

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trf4-1	NP_572490.2	TRF4	271..>583	CDD:227585	228/314 (73%)
LOC1281604	XP_321547.4	None