Protein Alignment CG32260 and TMPRSS5

DIOPT Version :10

• Sequence 1: NP_728942.1
• Gene: CG32260 / 317943
• FlyBaseID: FBgn0052260
• Length: 575
• Species: Drosophila melanogaster
• Sequence 2: NP_110397.2
• Gene: TMPRSS5 / 80975
• HGNCID: 14908
• Length: 457
• Species: Homo sapiens
• Alignment Length: 285
• Identity: 98/285 - (34%)
• Similarity: 142/285 - (49%)
• Gaps: 56/285 - (19%)

  Fly   312 PRESAT--------CGISGA--TSNRVVGGMEARKGAYPWIA--ALGYFEENNRNALKFLCGGSL 364
            ||.:.|        |...||  .::|:|||.....|.:||.|  |||:         :..||||:
Human   192 PRNNCTSGQVVSLRCSECGARPLASRIVGGQSVAPGRWPWQASVALGF---------RHTCGGSV 247

  Fly   365 IHSRYVITSAHCINPMLTLVRLG---------AHDLSQPAESGAMDLRIRRTVVHEHFDLNSISN 420
            :..|:|:|:|||:: ...|.||.         :|...:| ..||:   :.|.:.|..:...:...
Human   248 LAPRWVVTAAHCMH-SFRLARLSSWRVHAGLVSHSAVRP-HQGAL---VERIIPHPLYSAQNHDY 307

  Fly   421 DIALIELNVVGALPGNISPICLPEAAKFMQQDF-VGMNPFVAGWGAVKHQGVT--SQVLRDAQVP 482
            |:||:.|.........:..:|||  ||  :|.| .|...:|:|||.. |...|  |.:|:|..||
Human   308 DVALLRLQTALNFSDTVGAVCLP--AK--EQHFPKGSRCWVSGWGHT-HPSHTYSSDMLQDTVVP 367

  Fly   483 IVSRHSCEQS--YKSIFQFVQFSDKVLCAG--SSSVDACQGDSGGPLMMPQLEGNVYRFYLLGLV 543
            :.|...|..|  |..     ..:.::||||  ....|||||||||||:.|  :|:.:|  |:|:|
Human   368 LFSTQLCNSSCVYSG-----ALTPRMLCAGYLDGRADACQGDSGGPLVCP--DGDTWR--LVGVV 423

  Fly   544 SFGYECARPNFPGVYTRVASYVPWI 568
            |:|..||.||.||||.:||.::.||
Human   424 SWGRGCAEPNHPGVYAKVAEFLDWI 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32260	NP_728942.1	CLIP	194..244	CDD:463440
		Tryp_SPc	328..571	CDD:238113	91/259 (35%)
TMPRSS5	NP_110397.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21
		SRCR_2	116..213	CDD:464747	6/20 (30%)
		Tryp_SPc	217..448	CDD:214473	90/258 (35%)