DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32260 and Ctrc

DIOPT Version :9

Sequence 1:	NP_728942.1	Gene:	CG32260 / 317943	FlyBaseID:	FBgn0052260	Length:	575	Species:	Drosophila melanogaster
Sequence 2:	NP_001029047.1	Gene:	Ctrc / 76701	MGIID:	1923951	Length:	268	Species:	Mus musculus

Alignment Length:	274	Identity:	95/274 - (34%)
Similarity:	145/274 - (52%)	Gaps:	32/274 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   304 PPPPPNNAPRESATCGISGATSNRVVGGMEARKGAYPWIAALGYFEENNRNALKFLCGGSLIHSR 368
            |..|||              .|.|||||.:|...::||..:|.|..:   :..:..||||||.:.
Mouse    20 PTFPPN--------------LSARVVGGEDAVPNSWPWQVSLQYLRD---DTWRHTCGGSLITTS 67

  Fly   369 YVITSAHCINPMLTL-VRLGAHDLSQPAESGAMDLRIRRTVVHEHFDLNSISNDIALIELNVVGA 432
            :|:|:|||||..||. |.||.::|:...|.|::...:....|||.::...:.||||:|:|.....
Mouse    68 HVLTAAHCINTNLTYRVGLGKYNLTVEDEEGSVYAEVDTIYVHEKWNRLLLWNDIAIIKLAEPVE 132

  Fly   433 LPGNISPICLPEAAKFMQQDFVGMNP-FVAGWGAVKHQGVTSQVLRDAQVPIVSRHSCEQSYKSI 496
            |...|...|:||....:..|:    | :|.|||.:...|..::||:....|||:..:|.   :..
Mouse   133 LSDTIQVACIPEQDSLLPGDY----PCYVTGWGRLWTNGPIAEVLQQGLQPIVNHTTCS---RLD 190

  Fly   497 FQFVQFSDKVLCAGSSSV-DACQGDSGGPLMMPQLEGNVYRFYLLGLVSFGYE--CARPNFPGVY 558
            :.|::..:.::|||...| .||.|||||||..| :|..:::.:  |:||||..  |.....|.|:
Mouse   191 WWFIKVRETMVCAGGDGVISACNGDSGGPLNCP-VEDGLWQVH--GIVSFGSSRGCNTYKKPVVF 252

  Fly   559 TRVASYVPWIKKHI 572
            |||::|:.|||:.|
Mouse   253 TRVSAYIDWIKEKI 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32260	NP_728942.1	CLIP	194..244	CDD:288855
		Tryp_SPc	327..568	CDD:214473	86/245 (35%)
		Tryp_SPc	328..571	CDD:238113	88/247 (36%)
Ctrc	NP_001029047.1	Tryp_SPc	29..262	CDD:214473	86/245 (35%)
Ctrc	NP_001029047.1	Tryp_SPc	30..265	CDD:238113	88/247 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R8300
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940