DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32260 and Prss21

DIOPT Version :9

Sequence 1:	NP_728942.1	Gene:	CG32260 / 317943	FlyBaseID:	FBgn0052260	Length:	575	Species:	Drosophila melanogaster
Sequence 2:	NP_065233.2	Gene:	Prss21 / 57256	MGIID:	1916698	Length:	324	Species:	Mus musculus

Alignment Length:	307	Identity:	95/307 - (30%)
Similarity:	144/307 - (46%)	Gaps:	33/307 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   277 GSTATPMVFQPTPPLSQVVSPSFYPPPPPPPPNNAPRESATCGISGATSNRVVGGMEARKGAYPW 341
            |.|..|::.........:.|......|..|........|..|| .....:|:|||.:|..|.:||
Mouse     5 GKTLVPLLVVVATAAMALQSTYLQVDPEKPELQEPDLLSGPCG-HRTIPSRIVGGDDAELGRWPW 68

  Fly   342 IAALGYFEENNRNALKFLCGGSLIHSRYVITSAHCI----NPMLTLVRLGAHDLSQPAESGAMDL 402
            ..:|..:..:       |||.:|::.|:|:|:|||.    :|....|:.|  :|:.......:..
Mouse    69 QGSLRVWGNH-------LCGATLLNRRWVLTAAHCFQKDNDPFDWTVQFG--ELTSRPSLWNLQA 124

  Fly   403 RIRRTVVHEHFDLNSIS----NDIALIELNVVGALPGNISPICLPEAA-KFMQQDFVGMNPFVAG 462
            ...|..:.:.|.....|    |||||::|:........|.||||..:. ||..:    .:.:|.|
Mouse   125 YSNRYQIEDIFLSPKYSEQYPNDIALLKLSSPVTYNNFIQPICLLNSTYKFENR----TDCWVTG 185

  Fly   463 WGAV-KHQGVTS-QVLRDAQVPIVSRHSCEQSYKS-IFQFVQFSDKVLCAGS--SSVDACQGDSG 522
            |||: :.:.:.| ..|::.||.|::...|...||. .|:...:.|.| |||:  ...|||.||||
Mouse   186 WGAIGEDESLPSPNTLQEVQVAIINNSMCNHMYKKPDFRTNIWGDMV-CAGTPEGGKDACFGDSG 249

  Fly   523 GPLMMPQLEGNVYRFYLLGLVSFGYECARPNFPGVYTRVASYVPWIK 569
            |||...|  ..|:  |.:|:||:|..|.|||.|||||.::.:..||:
Mouse   250 GPLACDQ--DTVW--YQVGVVSWGIGCGRPNRPGVYTNISHHYNWIQ 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32260	NP_728942.1	CLIP	194..244	CDD:288855
		Tryp_SPc	327..568	CDD:214473	84/254 (33%)
		Tryp_SPc	328..571	CDD:238113	85/256 (33%)
Prss21	NP_065233.2	Tryp_SPc	54..291	CDD:214473	84/254 (33%)
Prss21	NP_065233.2	Tryp_SPc	55..294	CDD:238113	85/256 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910