Protein Alignment CG32260 and PRSS3

DIOPT Version :10

• Sequence 1: NP_728942.1
• Gene: CG32260 / 317943
• FlyBaseID: FBgn0052260
• Length: 575
• Species: Drosophila melanogaster
• Sequence 2: NP_001184026.3
• Gene: PRSS3 / 5646
• HGNCID: 9486
• Length: 261
• Species: Homo sapiens
• Alignment Length: 313
• Identity: 87/313 - (27%)
• Similarity: 139/313 - (44%)
• Gaps: 63/313 - (20%)

  Fly   270 HFSPLSG-----GSTATPMVFQPTPPLSQVVSPSFYPPPPPPPPNNAPRESATCGISGATSNRVV 329
            |....||     |.:| |:||.|...|..|                 |.:.         .:::|
Human     2 HMRETSGFTLKKGRSA-PLVFHPPDALIAV-----------------PFDD---------DDKIV 39

  Fly   330 GGMEARKGAYPWIAALGYFEENNRNALKFLCGGSLIHSRYVITSAHCINPMLTLVRLGAHDLSQP 394
            ||....:.:.|:..:|        |:....||||||..::|:::|||....:. ||||.|:: :.
Human    40 GGYTCEENSLPYQVSL--------NSGSHFCGGSLISEQWVVSAAHCYKTRIQ-VRLGEHNI-KV 94

  Fly   395 AESGAMDLRIRRTVVHEHFDLNSISNDIALIELNVVGALPGNISPICLPEAAKFMQQDFVGMNPF 459
            .|.....:...:.:.|..::.:::.|||.||:|:....:...:|.|.||..     ....|....
Human    95 LEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTT-----PPAAGTECL 154

  Fly   460 VAGWGAVKHQGVT-SQVLRDAQVPIVSRHSCEQSYKSIFQFVQFSDKVLCAG--SSSVDACQGDS 521
            ::|||.....|.. ...|:....|::::..|:.||..     :.::.:.|.|  ....|:||.||
Human   155 ISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPG-----KITNSMFCVGFLEGGKDSCQRDS 214

  Fly   522 GGPLMMPQLEGNVYRFYLLGLVSFGYECARPNFPGVYTRVASYVPWIKKHIAS 574
            |||:        |....|.|:||:|:.||..|.|||||:|.:||.|||..||:
Human   215 GGPV--------VCNGQLQGVVSWGHGCAWKNRPGVYTKVYNYVDWIKDTIAA 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32260	NP_728942.1	CLIP	194..244	CDD:463440
		Tryp_SPc	328..571	CDD:238113	73/245 (30%)
PRSS3	NP_001184026.3	Tryp_SPc	38..256	CDD:238113	73/245 (30%)