DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32260 and cela1.6

DIOPT Version :9

Sequence 1:	NP_728942.1	Gene:	CG32260 / 317943	FlyBaseID:	FBgn0052260	Length:	575	Species:	Drosophila melanogaster
Sequence 2:	NP_001003737.1	Gene:	cela1.6 / 445282	ZFINID:	ZDB-GENE-040808-55	Length:	266	Species:	Danio rerio

Alignment Length:	250	Identity:	77/250 - (30%)
Similarity:	130/250 - (52%)	Gaps:	25/250 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   327 RVVGGMEARKGAYPWIAALGYFEENNRNALKFLCGGSLIHSRYVITSAHCINPMLT-LVRLGAHD 390
            |||||..||..::||..:|.|.   :..:....|||:||...:|:|:|||::...| .|.||.||
Zfish    29 RVVGGEVARPNSWPWQISLQYL---SGGSYYHTCGGTLIKQNFVLTAAHCVDTSRTWRVVLGEHD 90

  Fly   391 LSQPAESGAMDLRIRRTVVHEHFDLNSIS--NDIALIELNVVGALPGNISPICLPEAAKFMQQDF 453
            :.: .|.....:.:....:|.:::.|:::  .||||:.|:...:|...:....||.:.:.:..:
Zfish    91 IYK-QEGREQYMTVSNVYIHPNWNRNNVAAGYDIALLRLSSNASLNTYVQLGTLPPSGQVLPHN- 153

  Fly   454 VGMNP-FVAGWGAVKHQGVTSQVLRDAQVPIVSRHSCEQS--YKSIFQFVQFSDKVLCAGSSSVD 515
               |. ::.|||.....|..|..|:.|.:|:|..::|.:.  :.|..:     :.::|||..|:.
Zfish   154 ---NACYITGWGLTSTGGSLSAQLKQAYLPVVDYNTCSRGDWWGSTVK-----NTMVCAGGGSLS 210

  Fly   516 ACQGDSGGPLMMPQLEGNVYRFYLLGLVSF--GYECARPNFPGVYTRVASYVPWI 568
            .|||||||||.. |:.|   ::.:.|:.||  ...|.....|.|:|||::|:.||
Zfish   211 GCQGDSGGPLNC-QVSG---QYVVHGVTSFVSSSGCNAYQKPTVFTRVSAYISWI 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32260	NP_728942.1	CLIP	194..244	CDD:288855
		Tryp_SPc	327..568	CDD:214473	75/248 (30%)
		Tryp_SPc	328..571	CDD:238113	75/248 (30%)
cela1.6	NP_001003737.1	Tryp_SPc	30..264	CDD:238113	75/248 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	154	1.000	Domainoid score	I4208
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm24991
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910