DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32260 and cela1.3

DIOPT Version :9

Sequence 1:	NP_728942.1	Gene:	CG32260 / 317943	FlyBaseID:	FBgn0052260	Length:	575	Species:	Drosophila melanogaster
Sequence 2:	XP_021324991.1	Gene:	cela1.3 / 445032	ZFINID:	ZDB-GENE-040801-12	Length:	283	Species:	Danio rerio

Alignment Length:	265	Identity:	83/265 - (31%)
Similarity:	138/265 - (52%)	Gaps:	29/265 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   312 PRESATCGISGATSNRVVGGMEARKGAYPWIAALGYFEENNRNALKFLCGGSLIHSRYVITSAHC 376
            ||......|.|    |||||..|:..::||..:|.|.   :.::....||||||...:|:|:|||
Zfish    33 PRYLEDIDIEG----RVVGGEVAKPNSWPWQISLQYL---SGSSYYHTCGGSLIRPGWVMTAAHC 90

  Fly   377 I-NPMLTLVRLGAHDLSQPAESGAMDLRIRRTVVHEHFDLNSISN--DIALIELNVVGALPGNIS 438
            : :|....|.||.||:.. .|.....:.:.|..:|.:::.||:|:  ||||:||:...:|...:.
Zfish    91 VDSPRTWRVVLGDHDIYN-HEGREQYISVSRAHIHPNWNSNSLSSGYDIALLELSSDASLNSYVQ 154

  Fly   439 PICLPEAAKFMQQDFVGMNP-FVAGWGAVKHQGVTSQVLRDAQVPIVSRHSCEQS--YKSIFQFV 500
            ...||.:.:.:..:    || :::|||..:..|..|..|:.|.:|:|...:|.:|  :.|..:
Zfish   155 LAALPPSGQVLPNN----NPCYISGWGRTQTGGSLSAELKQAYLPVVDHDTCSRSDWWGSTVK-- 213

  Fly   501 QFSDKVLCAGSSSVDACQGDSGGPLMMPQLEGNVYRFYLLGLVSF--GYECARPNFPGVYTRVAS 563
               :.::|.|..::..|.|||||||.. |:.|   ::.:.|:.||  ...|.....|.|::||::
Zfish   214 ---NTMICGGDGTLAGCHGDSGGPLNC-QVSG---QYVVHGVTSFVSSAGCNTNKRPTVFSRVSA 271

  Fly   564 YVPWI 568
            |:.||
Zfish   272 YISWI 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32260	NP_728942.1	CLIP	194..244	CDD:288855
		Tryp_SPc	327..568	CDD:214473	77/248 (31%)
		Tryp_SPc	328..571	CDD:238113	78/249 (31%)
cela1.3	XP_021324991.1	Tryp_SPc	45..279	CDD:238113	78/249 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	154	1.000	Domainoid score	I4208
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm24991
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910