DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32260 and ela2

DIOPT Version :9

Sequence 1:	NP_728942.1	Gene:	CG32260 / 317943	FlyBaseID:	FBgn0052260	Length:	575	Species:	Drosophila melanogaster
Sequence 2:	NP_001132936.1	Gene:	ela2 / 403061	ZFINID:	ZDB-GENE-041117-1	Length:	266	Species:	Danio rerio

Alignment Length:	253	Identity:	95/253 - (37%)
Similarity:	146/253 - (57%)	Gaps:	17/253 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   326 NRVVGGMEARKGAYPWIAALGYFEENNRNALKFLCGGSLIHSRYVITSAHCINPMLTLVRLGAHD 390
            :|||||.:.|..::||.|:|.|   .:.::....|||:||..::|:|:||||:.....|.||.|:
Zfish    26 SRVVGGSDVRPNSWPWQASLQY---QSGSSFYHTCGGTLIDKQWVLTAAHCISSRTYRVLLGKHN 87

  Fly   391 LSQPAESGAMDLRIRRTVVHEHFDLNSISNDIALIELNVVGALPGNISPICLPEAAKFMQQDFVG 455
            |...:|||:..:...|.:|||::|..:|.||||||:|:........|||.|||::...:..:
Zfish    88 LPLSSESGSQAISPARIIVHENWDSYNIRNDIALIKLSTPVTFTDKISPACLPDSGSILPHN--- 149

  Fly   456 MNP-FVAGWGAVKHQGVTSQVLRDAQVPIVSRHSCEQSYKSIFQFVQFSDKVLCAGSSS-VDACQ 518
             :| :|.|||.:...|..:.:|:.|.:|||.:.:|.   ||.:.....:|.::|||... |.:|.
Zfish   150 -SPCYVTGWGRLWTGGPIADILQQALLPIVDQATCT---KSDWWGNLVTDLMVCAGGDGVVSSCN 210

  Fly   519 GDSGGPLMMPQLEGNVYRFYLLGLVSFGYE--CARPNFPGVYTRVASYVPWIKKHIAS 574
            |||||||...:.:|.   :.:.|:||||..  |..|..|.|:|||:.|:|||.|.:.|
Zfish   211 GDSGGPLNCQRRDGT---WDVHGIVSFGSSLGCNYPKKPSVFTRVSGYIPWINKVMTS 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32260	NP_728942.1	CLIP	194..244	CDD:288855
		Tryp_SPc	327..568	CDD:214473	91/244 (37%)
		Tryp_SPc	328..571	CDD:238113	92/246 (37%)
ela2	NP_001132936.1	Tryp_SPc	27..259	CDD:214473	91/244 (37%)
ela2	NP_001132936.1	Tryp_SPc	28..262	CDD:238113	92/246 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	154	1.000	Domainoid score	I4208
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm24991
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R8300
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.940