Protein Alignment CG32260 and KLKB1

DIOPT Version :10

• Sequence 1: NP_728942.1
• Gene: CG32260 / 317943
• FlyBaseID: FBgn0052260
• Length: 575
• Species: Drosophila melanogaster
• Sequence 2: XP_011530232.1
• Gene: KLKB1 / 3818
• HGNCID: 6371
• Length: 649
• Species: Homo sapiens
• Alignment Length: 272
• Identity: 89/272 - (32%)
• Similarity: 148/272 - (54%)
• Gaps: 32/272 - (11%)

  Fly   314 ESATCGISGATSNRVVGGMEARKGAYPWIAALGYFEENNRNALKFLCGGSLIHSRYVITSAHCIN 378
            :::.|  :..||.|:|||..:..|.:||..:|    :....|.:.|||||||..::|:|:|||.:
Human   390 DNSVC--TTKTSTRIVGGTNSSWGEWPWQVSL----QVKLTAQRHLCGGSLIGHQWVLTAAHCFD 448

  Fly   379 --PMLTLVRL--GAHDLSQPAESGAMDLRIRRTVVHEHFDLNSISNDIALIELNVVGALPGNIS- 438
              |:..:.|:  |..:||...:..... :|:..::|:::.::..::|||||:|..    |.|.:
Human   449 GLPLQDVWRIYSGILNLSDITKDTPFS-QIKEIIIHQNYKVSEGNHDIALIKLQA----PLNYTE 508

  Fly   439 ---PICLPEAAKFMQQDFVGMNPFVAGWGAVKHQGVTSQVLRDAQVPIVSRHSCEQSYKSIFQFV 500
               |||||...   ....:..|.:|.|||..|.:|....:|:...:|:|:...|::.|    |..
Human   509 FQKPICLPSKG---DTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRY----QDY 566

  Fly   501 QFSDKVLCAG--SSSVDACQGDSGGPLMMPQLEGNVYRFYLLGLVSFGYECARPNFPGVYTRVAS 563
            :.:.:::|||  ....|||:|||||||:..  ...::|  |:|:.|:|..|||...|||||:||.
Human   567 KITQRMVCAGYKEGGKDACKGDSGGPLVCK--HNGMWR--LVGITSWGEGCARREQPGVYTKVAE 627

  Fly   564 YVPWIKKHIASA 575
            |:.||.:...|:
Human   628 YMDWILEKTQSS 639

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32260	NP_728942.1	CLIP	194..244	CDD:463440
		Tryp_SPc	328..571	CDD:238113	84/252 (33%)
KLKB1	XP_011530232.1	APPLE	21..104	CDD:128519
		APPLE	111..194	CDD:128519
		APPLE	212..295	CDD:128519
		APPLE	303..386	CDD:128519
		Tryp_SPc	402..632	CDD:238113	82/249 (33%)