DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32260 and Prss21

DIOPT Version :9

Sequence 1:	NP_728942.1	Gene:	CG32260 / 317943	FlyBaseID:	FBgn0052260	Length:	575	Species:	Drosophila melanogaster
Sequence 2:	XP_006245934.1	Gene:	Prss21 / 353251	RGDID:	727870	Length:	337	Species:	Rattus norvegicus

Alignment Length:	327	Identity:	97/327 - (29%)
Similarity:	145/327 - (44%)	Gaps:	61/327 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   277 GSTATPMV---------FQPTPPLSQVVSPSFYPPPPPPPPNNAPRESATCGISGATSNRVVGGM 332
            |.|..|::         .|.|   |..|.|   ..|..|....|...|..|| .....:|:|||.
  Rat     5 GKTLVPLLVVVVAVEVTLQST---SSHVKP---VDPEKPELQEANLLSGPCG-HRTIPSRIVGGE 62

  Fly   333 EARKGAYPWIAALGYFEENNRNALKFLCGGSLIHSRYVITSAHCI----NPMLTLVRLGAHDLSQ 393
            ||..|.:||..:|..:..:       |||.:|::.|:|:|:|||.    :|....|:.|  :|:.
  Rat    63 EAELGRWPWQGSLRVWGNH-------LCGATLLNRRWVLTAAHCFQKDNDPFDWTVQFG--ELTS 118

  Fly   394 PAESGAMDLRIRRTVVHEHF----DLNSISNDIALIELNVVGALPGNISPICLPEAA-KFMQQDF 453
            ......:.....|..:.:.|    ......:||||::|:........|.||||..:. ||..:
  Rat   119 RPSLWNLQAYSNRYQIEDIFLSPKYTEQFPHDIALLKLSSPVTYSNFIQPICLLNSTYKFANR-- 181

  Fly   454 VGMNPFVAGWGAVKHQGVTSQV-----LRDAQVPIVSRHSCEQSYKSIFQFVQFSDKVLCAGS-- 511
              .:.:|.||||:   |....:     |::.||.|::...|...:|.....:.....::||||
  Rat   182 --TDCWVTGWGAI---GEDESLPLPNNLQEVQVAIINNTMCNHLFKKPDFRINIWGDMVCAGSPE 241

  Fly   512 SSVDAC---------QGDSGGPLMMPQLEGNVYRFYLLGLVSFGYECARPNFPGVYTRVASYVPW 567
            ...|||         ||||||||:..|  ..|:  |.:|:||:|..|.|||.|||||.::.:..|
  Rat   242 GGKDACFAKLTYAAPQGDSGGPLVCNQ--DTVW--YQVGVVSWGIGCGRPNRPGVYTNISHHYNW 302

  Fly   568 IK 569
            |:
  Rat   303 IR 304

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32260	NP_728942.1	CLIP	194..244	CDD:288855
		Tryp_SPc	327..568	CDD:214473	81/265 (31%)
		Tryp_SPc	328..571	CDD:238113	82/267 (31%)
Prss21	XP_006245934.1	Tryp_SPc	57..303	CDD:214473	81/265 (31%)
Prss21	XP_006245934.1	Tryp_SPc	58..304	CDD:238113	81/265 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910