DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32260 and ela2l

DIOPT Version :9

Sequence 1:	NP_728942.1	Gene:	CG32260 / 317943	FlyBaseID:	FBgn0052260	Length:	575	Species:	Drosophila melanogaster
Sequence 2:	NP_956180.1	Gene:	ela2l / 334304	ZFINID:	ZDB-GENE-040511-1	Length:	267	Species:	Danio rerio

Alignment Length:	265	Identity:	98/265 - (36%)
Similarity:	146/265 - (55%)	Gaps:	21/265 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   317 TCGIS--GATSNRVVGGMEARKGAYPWIAALGYFEENNRNALKFLCGGSLIHSRYVITSAHCINP 379
            :||:.  .....|||||::.|..::||..:|.|...:|   ....||||||..::|:|:||||:.
Zfish    16 SCGLPTFPPIVTRVVGGVDVRPNSWPWQISLQYKSGSN---WYHTCGGSLIDKQWVLTAAHCISS 77

  Fly   380 MLTL-VRLGAHDLSQPAESGAMDLRIRRTVVHEHFDLNSISNDIALIELNVVGALPGNISPICLP 443
            ..|. |.||.|.||| .|:|::.:...:.:|||.::..:|.||||||:|.....:...|:|.|||
Zfish    78 SRTYRVFLGKHSLSQ-EENGSVAIGAGKIIVHEAWNSFTIRNDIALIKLETAVTIGDTITPACLP 141

  Fly   444 EAAKFMQQDFVGMNP-FVAGWGAVKHQGVTSQVLRDAQVPIVSRHSCEQSYKSIFQFVQFSDKVL 507
            ||...:..:    .| :|.|||.:...|..:.:|:.|.:|:|...:|.   ||.:...|.:..::
Zfish   142 EAGYVLPHN----APCYVTGWGRLYTNGPLADILQQALLPVVDHATCS---KSDWWGSQVTTSMV 199

  Fly   508 CAGSSSVDA-CQGDSGGPLMMPQLEGNVYRFYLLGLVSF--GYECARPNFPGVYTRVASYVPWIK 569
            |||...|.| |.|||||||.....:|   .:.:.|:|||  |..|.....|.|:|||::|..||.
Zfish   200 CAGGDGVVAGCDGDSGGPLNCAGSDG---AWEVHGIVSFGSGLSCNYNKKPTVFTRVSAYSDWIS 261

  Fly   570 KHIAS 574
            |::||
Zfish   262 KNMAS 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32260	NP_728942.1	CLIP	194..244	CDD:288855
		Tryp_SPc	327..568	CDD:214473	91/245 (37%)
		Tryp_SPc	328..571	CDD:238113	92/247 (37%)
ela2l	NP_956180.1	Tryp_SPc	28..260	CDD:214473	91/245 (37%)
ela2l	NP_956180.1	Tryp_SPc	29..263	CDD:238113	92/247 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	154	1.000	Domainoid score	I4208
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm24991
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910