DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32260 and Prss34

DIOPT Version :9

Sequence 1:	NP_728942.1	Gene:	CG32260 / 317943	FlyBaseID:	FBgn0052260	Length:	575	Species:	Drosophila melanogaster
Sequence 2:	NP_848459.1	Gene:	Prss34 / 328780	MGIID:	2681414	Length:	318	Species:	Mus musculus

Alignment Length:	278	Identity:	88/278 - (31%)
Similarity:	137/278 - (49%)	Gaps:	64/278 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   328 VVGGMEARKGAYPWIAALGYFE-ENNRNALKFLCGGSLIHSRYVITSAHCINP----------ML 381
            :|||.......:||..:|..:: |::|  .:..|||||||.::|:|:|||:.|          .:
Mouse    35 IVGGCPVSASRFPWQVSLRLYDMEHSR--WEHECGGSLIHPQWVLTAAHCVRPKEVEAYGVRVQV 97

  Fly   382 TLVRLGAHDLSQPAESGAMDLRIRRTVVHEHFDLNSISN---DIALIELNVVGALPGNISPICLP 443
            ..:||..:|         ..:::.:.:.|..|.....:.   ||||::|:....|..::.|:.||
Mouse    98 GQLRLYEND---------QLMKVVKIIRHPKFSEKLSARGGADIALLKLDTRVVLSEHVYPVSLP 153

  Fly   444 EAAKFMQQDFVGMNPFVAGWGAVK---------HQGVTSQVLRDAQVPIVSRHSCEQSYK----- 494
            .|:..:...   ...:|||||.::         |       ||:..||||..:.|||.|:
Mouse   154 AASLRISSK---KTCWVAGWGVIENYMPLPPPYH-------LREVAVPIVENNDCEQKYQTNSSS 208

  Fly   495 -SIFQFVQFSDKVLCAGSSSVDACQGDSGGPLMMPQLEGNVYR----FYLLGLVSFGYECARPNF 554
             |..:.::  |.:||||....|:|:.||||||        |.|    :..:|:||:|..|..|:|
Mouse   209 DSTTRIIK--DDMLCAGKEGRDSCKADSGGPL--------VCRWNCSWVQVGVVSWGIGCGLPDF 263

  Fly   555 PGVYTRVASYVPWIKKHI 572
            |||||||.|||.|||.::
Mouse   264 PGVYTRVMSYVSWIKCYV 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32260	NP_728942.1	CLIP	194..244	CDD:288855
		Tryp_SPc	327..568	CDD:214473	85/272 (31%)
		Tryp_SPc	328..571	CDD:238113	88/275 (32%)
Prss34	NP_848459.1	Tryp_SPc	35..278	CDD:238113	86/273 (32%)
Prss34	NP_848459.1	Tryp_SPc	35..277	CDD:214473	85/272 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910