Protein Alignment CG32260 and F12

DIOPT Version :10

• Sequence 1: NP_728942.1
• Gene: CG32260 / 317943
• FlyBaseID: FBgn0052260
• Length: 575
• Species: Drosophila melanogaster
• Sequence 2: NP_001014028.1
• Gene: F12 / 306761
• RGDID: 1359175
• Length: 603
• Species: Rattus norvegicus
• Alignment Length: 580
• Identity: 154/580 - (26%)
• Similarity: 223/580 - (38%)
• Gaps: 191/580 - (32%)

  Fly   141 GARP----LPNCP-------CIDPRQ-----QQNSP-------LLSSTGPQ-------------- 168
            |:||    .||..       |::|::     .::||       :.:..||.
  Rat    67 GSRPWCATTPNFDEDQQWGYCLEPKKVKDHCSKHSPCHKGGTCVNTPNGPHCLCPEHLTGKHCQR 131

  Fly   169 ---IGSDMMVFMPLN--------SGRRRRRRRRPQS-C-----QDARSRP----GSCL-----PL 207
               ..|.::.|...|        .|..|.:.:.||: |     |..|..|    |:||     .|
  Rat   132 EKCFESQLLKFFHENEIWFRTGPGGVARCQCKGPQAVCKLLTSQVCRVNPCLNGGTCLLVEDHRL 196

  Fly   208 TSCPQLMQEYQGQANEFHTFLGQSICGFDGSTFMVCCATDRS----GNARSR------------- 255
            ..||      .|.|..|        |..|   ....|..||.    |.|::.
  Rat   197 CHCP------AGYAGPF--------CDLD---LKATCYEDRGLSYRGQAKTTLSGAPCQRWASEA 244

  Fly   256 --KDVFVTTAAPFGFFHFSPLSGGSTAT-PMVFQ----------------PTPPLSQVVSPSFYP 301
              :::..|.|..:|..|.:........| |..:.                ..|.|:..|||..:.
  Rat   245 TYRNMTETQALSWGLGHHAFCRNPDNDTRPWCYVWSGDRLSWDYCDLEQCQMPTLTSPVSPESHD 309

  Fly   302 PPPPPPP--------------NNAPR--------ESATCG------ISGATSNRVVGGMEARKGA 338
            ...|.||              :|:.|        .:..||      :|  :..|||||:.|..|:
  Rat   310 MLKPRPPILQMPQFPSLSDALDNSTRNQNVVSRTSTVVCGQRFRKRLS--SLRRVVGGLVALPGS 372

  Fly   339 YPWIAALGYFEENNRNALKFLCGGSLIHSRYVITSAHCINPM-----LTLVRLGAHDLSQPAESG 398
            :|:|||| |:.::       .|.||||...:|:|:|||:...     ||:| ||....:|..|.
  Rat   373 HPYIAAL-YWGDS-------FCAGSLIDPCWVLTAAHCLQKRPAPEELTVV-LGQDRHNQSCER- 427

  Fly   399 AMDLRIRRTVVHEHFDLNSISNDIALIEL----NVVGALPGNISPICLPEAAKFMQQDFVGMNPF 459
            ...|.:....:||.|...:..:|:||:.|    |....|..::.|:|||.:|....:..:..
  Rat   428 CQTLAVHSYRLHEGFSSKTYQHDLALLRLRGRKNSCAILSPHVQPVCLPSSAAPPSETVLCE--- 489

  Fly   460 VAGWGAVKHQGVTSQ----VLRDAQVPIVSRHSCEQSYKSIFQFVQFSDKV----LCAG--SSSV 514
            |||||   ||...::    .|::||||.:|...|..|.       ...|.:    ||||  ....
  Rat   490 VAGWG---HQFEGAEEYATFLQEAQVPFISLDRCSSSN-------VHGDAILPGMLCAGFLEGGA 544

  Fly   515 DACQGDSGGPLMMPQLEGNVYR-FYLLGLVSFGYECARPNFPGVYTRVASYVPWIKKHIA 573
            |||||||||||:..  ||...| ..|.|::|:|..|...|.|||||.||:|:.||::|.|
  Rat   545 DACQGDSGGPLVCD--EGVTERQLTLRGVISWGSGCGDRNKPGVYTDVANYLDWIQEHTA 602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32260	NP_728942.1	CLIP	194..244	CDD:463440	15/63 (24%)
		Tryp_SPc	328..571	CDD:238113	94/262 (36%)
F12	NP_001014028.1	FN2	40..87	CDD:238019	5/19 (26%)
		EGF_CA	95..130	CDD:238011	4/34 (12%)
		FN1	132..170	CDD:238018	7/37 (19%)
		EGF	177..207	CDD:394967	10/35 (29%)
		Kringle	216..294	CDD:395005	11/77 (14%)
		Tryp_SPc	362..600	CDD:238113	94/262 (36%)