DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32260 and Prss8

DIOPT Version :9

Sequence 1:	NP_728942.1	Gene:	CG32260 / 317943	FlyBaseID:	FBgn0052260	Length:	575	Species:	Drosophila melanogaster
Sequence 2:	NP_620191.1	Gene:	Prss8 / 192107	RGDID:	619973	Length:	342	Species:	Rattus norvegicus

Alignment Length:	281	Identity:	98/281 - (34%)
Similarity:	142/281 - (50%)	Gaps:	52/281 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   316 ATCGISGATSNRVVGGMEARKGAYPWIAALGYFEENNRNALKFLCGGSLIHSRYVITSAHCI--- 377
            |:||  .....|:.||..|:.|.:||..::.|      |.: .:|||||:.:::|:::|||.
  Rat    35 ASCG--AVIQPRITGGGSAKPGQWPWQVSITY------NGV-HVCGGSLVSNQWVVSAAHCFPRE 90

  Fly   378 -NPMLTLVRLGAHDLSQPAESGAMDL---RIRRTVVHEHFDLNSISNDIALIELNVVGALPGNIS 438
             :.....|:||||.|    :|.:.|:   .:.:.:.|..:.......|||||.|:........|.
  Rat    91 HSKEEYEVKLGAHQL----DSFSNDIVVHTVAQIISHSSYREEGSQGDIALIRLSSPVTFSRYIR 151

  Fly   439 PICLPEA-AKFMQQDFVGMNPFVAGWG----AVKHQGVTSQVLRDAQVPIVSRHSCEQSYK---- 494
            |||||.| |.|..    |::..|.|||    :|..|  |.:.|:..:||::||.:|...|.
  Rat   152 PICLPAANASFPN----GLHCTVTGWGHVAPSVSLQ--TPRPLQQLEVPLISRETCSCLYNINAV 210

  Fly   495 -----SIFQFVQFSDKVLCAG--SSSVDACQGDSGGPLMMPQLEGNVYRFYLLGLVSFGYECARP 552
                 :|.|      .:||||  ....|||||||||||..| ::|   .:||.|:||:|..|..|
  Rat   211 PEEPHTIQQ------DMLCAGYVKGGKDACQGDSGGPLSCP-IDG---LWYLAGIVSWGDACGAP 265

  Fly   553 NFPGVYTRVASYVPWIKKHIA 573
            |.|||||..::|..||..|:|
  Rat   266 NRPGVYTLTSTYASWIHHHVA 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32260	NP_728942.1	CLIP	194..244	CDD:288855
		Tryp_SPc	327..568	CDD:214473	91/263 (35%)
		Tryp_SPc	328..571	CDD:238113	92/265 (35%)
Prss8	NP_620191.1	Tryp_SPc	44..281	CDD:214473	91/263 (35%)
Prss8	NP_620191.1	Tryp_SPc	45..284	CDD:238113	92/265 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910