DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32260 and Cela2a

DIOPT Version :9

Sequence 1:	NP_728942.1	Gene:	CG32260 / 317943	FlyBaseID:	FBgn0052260	Length:	575	Species:	Drosophila melanogaster
Sequence 2:	NP_031945.1	Gene:	Cela2a / 13706	MGIID:	95316	Length:	271	Species:	Mus musculus

Alignment Length:	283	Identity:	94/283 - (33%)
Similarity:	143/283 - (50%)	Gaps:	53/283 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   320 ISGATS------------NRVVGGMEARKGAYPWIAAL-----GYFEENNRNALKFLCGGSLIHS 367
            ::||.|            :|||||.||....:||..:|     |.:..|        |||||:.:
Mouse    11 VAGALSCGYPTYEVEDDVSRVVGGQEATPNTWPWQVSLQVLSSGRWRHN--------CGGSLVAN 67

  Fly   368 RYVITSAHCINPMLTL-VRLGAHDLSQPAESGAMDLRIRRTVVHEHFDLNSISN--DIALIELNV 429
            .:|:|:|||::...|. |.||||.||.|. :|:..:::.:.|||:.::..::.|  |||||:|..
Mouse    68 NWVLTAAHCLSNYQTYRVLLGAHSLSNPG-AGSAAVQVSKLVVHQRWNSQNVGNGYDIALIKLAS 131

  Fly   430 VGALPGNISPICLPEAAKFMQQDFVGMNPFVAGWGAVKHQGVTSQVLRDAQVPIVSRHSCE---- 490
            ...|..||...|||.|...:.:::|   .:|.|||.::..|.:...||..::.:|...:|.
Mouse   132 PVTLSKNIQTACLPPAGTILPRNYV---CYVTGWGLLQTNGNSPDTLRQGRLLVVDYATCSSASW 193

  Fly   491 --QSYKSIFQFVQFSDKVLCAGSSSV-DACQGDSGGPLMMPQLEGNVYRFYLLGLVSFGYE--CA 550
              .|.||         .::|||...| .:|.|||||||......|   ::.:.|:||||..  |.
Mouse   194 WGSSVKS---------SMVCAGGDGVTSSCNGDSGGPLNCRASNG---QWQVHGIVSFGSSLGCN 246

  Fly   551 RPNFPGVYTRVASYVPWIKKHIA 573
            .|..|.|:|||::|:.||...:|
Mouse   247 YPRKPSVFTRVSNYIDWINSVMA 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32260	NP_728942.1	CLIP	194..244	CDD:288855
		Tryp_SPc	327..568	CDD:214473	88/257 (34%)
		Tryp_SPc	328..571	CDD:238113	89/259 (34%)
Cela2a	NP_031945.1	Tryp_SPc	30..264	CDD:214473	88/257 (34%)
Cela2a	NP_031945.1	Tryp_SPc	31..267	CDD:238113	89/259 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R8300
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940