DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32260 and CTRC

DIOPT Version :9

Sequence 1:	NP_728942.1	Gene:	CG32260 / 317943	FlyBaseID:	FBgn0052260	Length:	575	Species:	Drosophila melanogaster
Sequence 2:	XP_011538852.1	Gene:	CTRC / 11330	HGNCID:	2523	Length:	280	Species:	Homo sapiens

Alignment Length:	155	Identity:	53/155 - (34%)
Similarity:	85/155 - (54%)	Gaps:	12/155 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   315 SATCGISGATSN---RVVGGMEARKGAYPWIAALGYFEENNRNALKFLCGGSLIHSRYVITSAHC 376
            :::||:.....|   |||||.:||..::||..:|.|.:   .:..:..|||:||.|.:|:|:|||
Human    14 ASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLK---NDTWRHTCGGTLIASNFVLTAAHC 75

  Fly   377 INPMLTL-VRLGAHDLSQPAESGAMDLRIRRTVVHEHFDLNSISNDIALIELNVVGALPGNISPI 440
            |:...|. |.:|.::|....|.|::.:.:....||:.::...:.||||||:|.....|...|...
Human    76 ISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVA 140

  Fly   441 CLPEAAKFMQQDFVGMNP-FVAGWG 464
            ||||....:.:|:    | :|.|||
Human   141 CLPEKDSLLPKDY----PCYVTGWG 161

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32260	NP_728942.1	CLIP	194..244	CDD:288855
		Tryp_SPc	327..568	CDD:214473	50/140 (36%)
		Tryp_SPc	328..571	CDD:238113	49/139 (35%)
CTRC	XP_011538852.1	Tryp_SPc	29..>163	CDD:214473	50/140 (36%)
CTRC	XP_011538852.1	Tryp_SPc	30..>173	CDD:238113	49/139 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R8300
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.940