Protein Alignment CG32260 and KLK11

DIOPT Version :10

• Sequence 1: NP_728942.1
• Gene: CG32260 / 317943
• FlyBaseID: FBgn0052260
• Length: 575
• Species: Drosophila melanogaster
• Sequence 2: XP_011524671.1
• Gene: KLK11 / 11012
• HGNCID: 6359
• Length: 307
• Species: Homo sapiens
• Alignment Length: 289
• Identity: 86/289 - (29%)
• Similarity: 132/289 - (45%)
• Gaps: 64/289 - (22%)

  Fly   316 ATCGISGATSNRVVGGMEARKGAYPWIAALGYFEENNRNALKFLCGGSLIHSRYVITSAHCINPM 380
            ||..:.|.|  |::.|.|.:..:.||.|||  ||:.     :.|||.:||..|:::|:|||:.|.
Human    44 ATGLVGGET--RIIKGFECKPHSQPWQAAL--FEKT-----RLLCGATLIAPRWLLTAAHCLKPW 99

  Fly   381 LTL------------------------VRLGAHDLSQPAESGAMDLR-IRRTVVHEHFDLNSI-- 418
            ::|                        |.||.|:|.:  |.|....| ...:..|..|: ||:
Human   100 VSLTSPTHVSPDLSSSNYCLSHLSRYIVHLGQHNLQK--EEGCEQTRTATESFPHPGFN-NSLPN 161

  Fly   419 ---SNDIALIELNVVGALPGNISPICLPEAAKFMQQDFVGMNPFVAGWGAVKH-QGVTSQVLRDA 479
               .|||.|:::....::...:.|:.|.....     ..|.:..::|||:... |......||.|
Human   162 KDHRNDIMLVKMASPVSITWAVRPLTLSSRCV-----TAGTSCLISGWGSTSSPQLRLPHTLRCA 221

  Fly   480 QVPIVSRHSCEQSYKSIFQFVQFSDKVLCAG--SSSVDACQGDSGGPLMMPQLEGNVYRFYLLGL 542
            .:.|:....||.:|..     ..:|.::||.  ....|:|||||||||:..|        .|.|:
Human   222 NITIIEHQKCENAYPG-----NITDTMVCASVQEGGKDSCQGDSGGPLVCNQ--------SLQGI 273

  Fly   543 VSFGYE-CARPNFPGVYTRVASYVPWIKK 570
            :|:|.: ||....|||||:|..||.||::
Human   274 ISWGQDPCAITRKPGVYTKVCKYVDWIQE 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32260	NP_728942.1	CLIP	194..244	CDD:463440
		Tryp_SPc	328..571	CDD:238113	81/277 (29%)
KLK11	XP_011524671.1	Tryp_SPc	53..300	CDD:214473	80/274 (29%)