DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32260 and tmprss12

DIOPT Version :9

Sequence 1:	NP_728942.1	Gene:	CG32260 / 317943	FlyBaseID:	FBgn0052260	Length:	575	Species:	Drosophila melanogaster
Sequence 2:	XP_031751504.1	Gene:	tmprss12 / 100127698	XenbaseID:	XB-GENE-964846	Length:	324	Species:	Xenopus tropicalis

Alignment Length:	274	Identity:	101/274 - (36%)
Similarity:	147/274 - (53%)	Gaps:	31/274 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   314 ESATCG---ISGATSNRVVGGMEARKGAYPWIAALGYFEENNRNALKFLCGGSLIHSRYVITSAH 375
            :|..||   :.....:|:|||..|..||:||..:|.||  ...:.....||||||.:.:|:::||
Frog    24 DSEVCGEPPLVHTPGSRIVGGRNALPGAWPWQVSLQYF--RTLSGYSHRCGGSLIQNNWVLSAAH 86

  Fly   376 CI----NPMLTLVRLGAHDLSQPAESGAMDLRIRRTVVHEHFDLNSISNDIALIELNVVGALPGN 436
            |.    ||......||.|::.... |..:..:|::.::|..:|..:|:|||||:.|:........
Frog    87 CFRANRNPEYWRAVLGLHNIFMEG-SPVVKAKIKQIIIHASYDHIAITNDIALLLLHDFVTYSDY 150

  Fly   437 ISPICL-----PEAAKFMQQDFVGMNPFVAGWGAVKHQGVTSQVLRDAQVPIVSRHSCEQSYKSI 496
            |.|:||     |::....         |:.|||..|.:|..|.:|::|.|..:....|..| .|.
Frog   151 IHPVCLGSVTVPDSLTAC---------FITGWGVTKEKGSISVILQEALVQTIPYSECNSS-SSY 205

  Fly   497 FQFVQFSDKVLCAG--SSSVDACQGDSGGPLMMPQLEGNVYRFYLLGLVSFGYECARPNFPGVYT 559
            ..|:  :..::|||  |.:||:||||||||.:....|.  .|||.:|:.||||.|.:||||||||
Frog   206 NGFI--TQSMICAGDNSGAVDSCQGDSGGPFVCYNTER--MRFYQMGITSFGYGCGKPNFPGVYT 266

  Fly   560 RVASYVPWIKKHIA 573
            :|.|||.|||.|:|
Frog   267 KVESYVSWIKAHMA 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32260	NP_728942.1	CLIP	194..244	CDD:288855
		Tryp_SPc	327..568	CDD:214473	93/251 (37%)
		Tryp_SPc	328..571	CDD:238113	95/253 (38%)
tmprss12	XP_031751504.1	Tryp_SPc	41..278	CDD:238113	95/253 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R8300
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940