DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32249 and SELPLG

DIOPT Version :9

Sequence 1:	NP_729001.2	Gene:	CG32249 / 317939	FlyBaseID:	FBgn0052249	Length:	242	Species:	Drosophila melanogaster
Sequence 2:	NP_001193538.1	Gene:	SELPLG / 6404	HGNCID:	10722	Length:	428	Species:	Homo sapiens

Alignment Length:	197	Identity:	34/197 - (17%)
Similarity:	64/197 - (32%)	Gaps:	23/197 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 PQIIERQVVPAPLVVPQVVPVYRPSPVVQIARPAPQVISVAAPRNTYLPP-QVISRPAPQVVSIA 110
            |:::.......||..|              ..|....:..||.|:|.|.. ..::....::.::.
Human    76 PEMLRNSTDTTPLTGP--------------GTPESTTVEPAARRSTGLDAGGAVTELTTELANMG 126

  Fly   111 R----PAPQVVSIARPAPQVVSIARPAPQVVSIARPAPQVVSIARPAPEVVSIARPAPEVVSIAR 171
            .    .|...:...:||.......:|.|   :.|:..|...:.|:......:.|:..|...:.|:
Human   127 NLSTDSAAMEIQTTQPAATEAQTTQPVP---TEAQTTPLAATEAQTTRLTATEAQTTPLAATEAQ 188

  Fly   172 PAPQVVSIARPA-PQVVSIARPAPQVVSIVRPAPQVVSIARPAPQVISVAAPRNTYLPPQVIAPR 235
            ..|...:.|:.. |..:.....||..:.....||..:......|..:.....:.|.:..|..||.
Human   189 TTPPAATEAQTTQPTGLEAQTTAPAAMEAQTTAPAAMEAQTTPPAAMEAQTTQTTAMEAQTTAPE 253

  Fly   236 NT 237
            .|
Human   254 AT 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32249	NP_729001.2	PRK07994	<101..>215	CDD:236138	18/118 (15%)
SELPLG	NP_001193538.1	rne	<136..295	CDD:236766	23/123 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5212
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.030